… protective adaptation to the tumor microenvironment. This notion … cells are less tumorigenic
than wild-type cells and that the resulting xenografts show slower growth. The slower tumor …

… , suppressing the ability to engage host anti-tumor immunity [83]. In the following sections,
we address approaches to manipulate apoptosis in the tumor microenvironment, as well as …

… of the tumor microenvironment causes differential activation of pro-survival and pro-death …
, stromal, endothelial and immune cells, hence causing a profound cellular and biological …

… of the tumor microenvironment (stromal and malignant cells) in cancer … cells but also cells
from the microenvironment such as fibroblasts, endothelial cells or mesenchymal stem cells. …

… the tumor microenvironment may provide a sanctuary for subpopulations of tumors cells that
… More specifically, we propose that the bone marrow microenvironment is a sanctuary for …

… immunogenic death of cancer cells can induce an effective anti-tumor immune … cell death
in the tumor microenvironment, and how these interact with host immune cells to impact tumor …

… enrichment of Tregs in the tumor microenvironment. nTregs are more resistant to oxidative
stress-mediated cell death compared to conventional CD4+ T cells from healthy individuals […

… cell death adds the cross-talk between cancer cells … of cell death evokes the expression of
distinct cell surface markers and the release of factors that shape the tumor microenvironment. …

… the relationship between cell death and PDT/ICD, we assessed cell apoptosis after … cells,
which probably caused ICD by preapoptotic exposure of CRT. IND scarcely caused cell death (…

T-cell exhaustion was originally identified during chronic infection in mice, and was subsequently
observed in humans with cancer. The exhausted T cells in the tumor microenvironment …