Past, present, and future of affinity-based cell separation technologies
… of the cell product. For most applications, the requisite purity is only achievable through affinity
… for developing cell-targeting affinity ligands and their application in cell purification, along …
… for developing cell-targeting affinity ligands and their application in cell purification, along …
Peptide dose, affinity, and time of differentiation can contribute to the Th1/Th2 cytokine balance
PR Rogers, M Croft - The Journal of Immunology, 1999 - journals.aai.org
… which T cells differentiate can be critical to whether Th1 or Th2 cells … affinity, is required
to generate T cells secreting IL-4 and IFN-γ, but only during the initial stages of the naive T cell …
to generate T cells secreting IL-4 and IFN-γ, but only during the initial stages of the naive T cell …
Breaking the affinity ceiling for antibodies and T cell receptors
J Foote, HN Eisen - … of the National Academy of Sciences, 2000 - National Acad Sciences
… affinity maturation of T lymphocytes at the level of cell populations by selection of the available
repertoire recently has been described (4). The affinities of antibodies … B and T cells, about …
repertoire recently has been described (4). The affinities of antibodies … B and T cells, about …
Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes
AF Williams, G Galfrè, C Milstein - Cell, 1977 - cell.com
… to study differentiation antigens by means of monoclonal xenogeneic antibodies produced
… It could be due to low antibody affinity since absorption analysis requires complete removal …
… It could be due to low antibody affinity since absorption analysis requires complete removal …
Affinity for self antigen selects Treg cells with distinct functional properties
L Wyss, BD Stadinski, CG King, S Schallenberg… - Nature …, 2016 - nature.com
… the affinity of the T cell antigen receptor for self antigen drives the differentiation of T reg cells
into … are distinct; this is expected if TCR specificity is linked to T reg cell differentiation. The …
into … are distinct; this is expected if TCR specificity is linked to T reg cell differentiation. The …
Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells
NJ Kräutler, D Suan, D Butt, K Bourne… - Journal of Experimental …, 2017 - rupress.org
… Nevertheless, the process whereby GC B cells differentiate into PCs is … PC differentiation
of only high-affinity GC B cells remains unknown. In this study, we show that differentiation into …
of only high-affinity GC B cells remains unknown. In this study, we show that differentiation into …
[HTML][HTML] The extent of affinity maturation differs between the memory and antibody‐forming cell compartments in the primary immune response
KGC Smith, A Light, GJV Nossal, DM Tarlinton - The EMBO journal, 1997 - embopress.org
… , the basis of the increasing affinity of serum antibody for antigen during the … ‐cell population
remain to be clarified. In this report we examine affinity maturation of antigen‐specific B cells …
remain to be clarified. In this report we examine affinity maturation of antigen‐specific B cells …
Antibody affinity may influence antigenic modulation of the common acute lymphoblastic leukemia antigen in vitro.
TW Lebien, DR Boué, JG Bradley… - Journal of immunology …, 1982 - journals.aai.org
… significant antigenic modulation of CALLA in vitro using fresh … cells and leukemic cell
lines. Thus, we suggest that antibody affinity may be a significant factor influencing antigenic …
lines. Thus, we suggest that antibody affinity may be a significant factor influencing antigenic …
B cell receptor affinity and B cell subset identity integrate to define the effectiveness, affinity threshold, and mechanism of anergy
R Diz, SK McCray, SH Clarke - The Journal of Immunology, 2008 - journals.aai.org
… affinity anti-Sm B cells differentiate into FO and MZ B cells, whereas low-affinity anti-Sm B cells
only differentiate into FO B cells … B cell differentiation than for FO B cell differentiation (32). …
only differentiate into FO B cells … B cell differentiation than for FO B cell differentiation (32). …
Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens
T Springer, G Galfre, DS Secher… - European journal of …, 1978 - Wiley Online Library
… M1/19.47 antibody has very low affinity, and it has not been identified as … antibodies to
differentiation antigens have been based on screening hybrid myeloma cultures with a similar cell …
differentiation antigens have been based on screening hybrid myeloma cultures with a similar cell …