… enriched for responsiveness to the B 2 CRBC antigen undergo marked proliferation.
Despite intense cell division, no significant degree of B cell differentiation into AFC is observed …

… affinity in the initial differentiation of PCs, we tracked Igh g2A10 cells specific for the malaria
vaccine antigen P… falciparum circumsporozoite protein (PfCSP) by single-cell RNA-seq in the …

… Anti-Sm B cells of 2-12H Tg mice differentiate to B-1 and … -affinity anti-Sm B cells differentiate
to B-1, we examined peritoneal cells of V κ 8 Dbl Tg mice for evidence of differentiation to B-…

… factor-p, are involved in B cell maturation and differentiation [12-17), but it is … affinity maturation
or B cell memory. Several of these cytokines are important not only for B cell differentiation…

… -cell resolution for individual antibody-secreting cells (ASC). Here, we tested the hypothesis
that antigen-… a diverse set of viral antigens if the standard direct (non-specific, low affinity) …

… Thus, our work demonstrates that, contrary to conventional wisdom, the plasma cell
differentiation pathway in the spleens of old animals is enhanced following T-dependent Ag …

… Cytokines produced by antigen-presenting cells (APC) or lymphocytes have been shown
to play an important role in helper T-cell differentiation. Thus, the presence of IL-4 or IL-12/IFN-'…

… of particulate antigen with respect to its dependence on antigen affinity. Analysis of the …
antigen was sensitive to antigen affinity even in the high (5 × 10 8 M −1 –5 × 10 10 M −1 ) affinity …

… , and lymphocyte differentiation antigens to characterize the differentiative state of Peyer's
patch germinal center cells. The … Affinity-purified rabbit antibodies against mouse p and K lg …

… role of these checkpoints in affinity selection and maturation, … B cells at these checkpoints
to discriminate antigen affinity or of the cellular and molecular mechanisms that facilitate affinity …