… of affinity … -81 antigen on the surface of hES cells, we attempt to address these issues in the
current study to establish a global quantitative method in probing membrane proteins on cells …

… trout, the B cell differentiation from activated B cells into … , the affinity partitioning ELISA was
employed to dissect affinity … to examine the affinity of IgM antibodies secreted by ASCs in vitro …

… cells carry a TCR that recognizes a ligand with low affinity 12 . To study how TCR affinity for
antigen … model in which TCR transgenic OT-1 cells are stimulated by different altered peptide …

… antigens). However, less is known about how the extent of this heterogeneity evolves with
time during affinity … heterogeneity (or affinity inequality), we analyzed antibodies isolated from …

… Since T cell tolerance in the periphery may be maintained by … -antigens with low affinity for
the TCR, we hypothesized that naive CD4 + T cells in lupus would be more likely than T cells …

… antibodies are found with higher affinities for analogues of the … B cells to discriminate among
closely related antigenic deter… monoclonal antibodies derived from both splenic B cells and …

… We reasoned that a low affinity TCR is more dependent on Fyn than a high affinity … the affinity
of the 2C TCR for various antigenic ligands has been determined. We used human T2 cells …

… GC B cells, we do not quite know how antigen affinity controls survival … antigen affinity has
a profound effect on B-cell differentiation. Cells with immediate high affinity directly differentiate …

… affinity T cells was due to oligoclonal expansion of a limited number of Ag-specific T cells or
represented a broader effect on the T cell … high- and low-affinity T cell clones using a panel of …

… In addition, we find that naive T cell differentiation into Th2 effector cells is impaired in the
absence of CD4. These data suggest that the altered pattern of biochemical signals generated …