Generating diversity: transcriptional regulation of effector and memory CD8+ T‐cell differentiation

RL Rutishauser, SM Kaech - Immunological reviews, 2010 - Wiley Online Library
… memory cell formation. We propose that the diversity of activated CD8 + T-cell differentiation
… by the level of inflammation and antigenic signaling the T cells experience during infection. …

Diversity in CD8+ T cell differentiation

IA Parish, SM Kaech - Current opinion in immunology, 2009 - Elsevier
diversity of CD8 + T cell responses to antigen, with a focus on recent work in the fields of CD8
+ T cell tolerance, effector cell differentiation … A model for generating diverse CD8 + T cell

Stem cells: the generation and maintenance of cellular diversity

PA Hall, FM Watt - Development, 1989 - journals.biologists.com
differentiated cell types or increase the total number of cells in the embryo. In contrast, the
major role of cell … number of differentiated cells at a constant level: to replace cells that have …

The generation of diversity and pattern in animal development

JB Gurdon - Cell, 1992 - Elsevier
… Mechanisms Initiating Cell Differentiation We now consider how embryonic cells first become
different on their way to a determined and ultimately differentiated state. There are some …

Generating diversity: Mechanisms regulating the differentiation of autonomic neuron phenotypes

KN Cane, CR Anderson - Autonomic Neuroscience, 2009 - Elsevier
generate such a diversity of neuronal phenotypes from the pool of apparently homogenous
neural crest progenitor cellsgenerated by both signals at the level of the cell body that trigger …

[HTML][HTML] Cell-intrinsic differences between stem cells from different regions of the peripheral nervous system regulate the generation of neural diversity

S Bixby, GM Kruger, JT Mosher, NM Joseph… - Neuron, 2002 - cell.com
… for neuronal differentiation even though only glia are generated in peripheral nerves … cell
types are generated in the nerve and gut as a result of cell-intrinsic differences in the stem cells

Diversity, topographic differentiation, and positional memory in human fibroblasts

HY Chang, JT Chi, S Dudoit… - Proceedings of the …, 2002 - National Acad Sciences
cells we call fibroblasts from different stromal sites may comprise a host of distinct differentiated
cell types, neither the diversity of these cells … environments generated by stromal cells (30…

Stem cell differentiation trajectories in Hydra resolved at single-cell resolution

S Siebert, JA Farrell, JF Cazet, Y Abeykoon… - Science, 2019 - science.org
… RNA sequencing permit identification of the complete molecular diversity of cell states in an
… Finally, we generated a molecular map of the nervous system with spatial resolution, which …

Generating neuronal diversity in the retina: one for nearly all

T Marquardt, P Gruss - Trends in neurosciences, 2002 - cell.com
… Several secreted factors are implicated in guiding RPCs towards different cell fates. Shh, for
… wave of cell differentiation by initiating the differentiation of the first cell type, ganglion cells, …

Engineered microenvironments for controlled stem cell differentiation

JA Burdick, G Vunjak-Novakovic - Tissue Engineering Part A, 2009 - liebertpub.com
… It has been argued that we need a new generation of 3D culture systems that would be “…
Alternatively, synthetic biomaterials have wide diversity in properties that may be obtained and …