Transcriptional control of effector and memory CD8+ T cell differentiation

SM Kaech, W Cui - Nature Reviews Immunology, 2012 - nature.com
… The expression or activity of counter-regulatory transcription factors functions in a graded
manner to regulate effector and memory T cell differentiation. Such transcription factor pairs …

Generating diversity: transcriptional regulation of effector and memory CD8+ T‐cell differentiation

RL Rutishauser, SM Kaech - Immunological reviews, 2010 - Wiley Online Library
… review, we focus on transcriptional control of cytotoxic CD8 + T-cell differentiation with a
particular … on the factors that regulate memory cell potential and terminal effector differentiation. …

[HTML][HTML] Transcriptional regulation of differentiation and functions of effector T regulatory cells

S Koizumi, H Ishikawa - Cells, 2019 - mdpi.com
… Upon antigen stimulation, cTreg cells differentiate into eTreg cells, … cells express higher
levels of Treg effector molecules, such as cytotoxic T cell antigen 4 (CTLA4) and inducible T cell

[HTML][HTML] Molecular regulation of effector and memory T cell differentiation

JT Chang, EJ Wherry, AW Goldrath - Nature immunology, 2014 - nature.com
regulate their accessibility to key sites of gene regulation, as well as metabolic regulators that
contribute to the differentiation of effector … exhibited by activated T cells. Collectively, these …

[HTML][HTML] Transcriptional and epigenetic regulation of effector and memory CD8 T cell differentiation

Y Chen, R Zander, A Khatun, DM Schauder… - Frontiers in …, 2018 - frontiersin.org
… factors that have been known to orchestrate CD8 T cell fate … CD8 T cell differentiation on the
epigenetic and single-cell level, … As cell identity determined by complicated gene regulatory

Distinct regulation of effector and memory T‐cell differentiation

A Kallies - Immunology and cell biology, 2008 - Wiley Online Library
… Recently, a number of elegant studies have revealed that the specificity in the function of
T-bet and Eomes resides at the level of their gene regulation. In these studies, IL12 has …

Transcriptional regulation of Th17 cell differentiation

II Ivanov, L Zhou, DR Littman - Seminars in immunology, 2007 - Elsevier
… The paradigm of effector T helper cell differentiation into either … transcriptional regulation
in the Th17 cell program awaits chromatin immunoprecipitation studies with these transcription

Transcriptional regulatory networks in Th17 cell differentiation

L Zhou, DR Littman - Current opinion in immunology, 2009 - Elsevier
… presenting cells, naïve CD4 + T cells undergo differentiation into effector T helper (Th) …
data on transcriptional regulatory networks that govern the differentiation program of Th17 cells, …

'All things considered': transcriptional regulation of T helper type 2 cell differentiation from precursor to effector activation

W Zeng - Immunology, 2013 - Wiley Online Library
… signalling, enhancers and the Th2 locus control region. This review provides a detailed
account of the transcriptional regulatory events at these different stages of Th2 differentiation. …

Recent developments in the transcriptional regulation of cytolytic effector cells

LH Glimcher, MJ Townsend, BM Sullivan… - Nature Reviews …, 2004 - nature.com
… about the transcriptional regulation of these pathways. Transcriptional regulation of perforin
gene expression. … Molecular and functional profiling of memory CD8 T cell differentiation. …