… This study uses real-world evidence to assess voxelotor’s effectiveness in SCD patients in
typical clinical practice from 2019 to 2021 using a national medical claims database (N = 3128…

… by the FDA for treating sickle cell disease (SCD). Voxelotor (… This study sought to assess
the real-world effectiveness of … This study sought to assess the real-world effectiveness of …

… Comparative effectiveness studies using real-world data (… and address potential bias in
comparative effectiveness study designs, robust … real-world evidence on treatment effectiveness. …

… outcomes and compare effectiveness in patients … in a real-world clinical setting in the United
Kingdom and Germany. Further, to our knowledge, this is the first multisite real-world efficacy …

… real-world patients on average aged 5 years older. Furthermore, we found that patients in the
real world … finding also may reflect a lower effectiveness of treatment in real-world practice. …

… disease are sufficiently similar in adults and children, regulatory agencies may conclude that
pediatric effectiveness … In such cases, regulatory agencies may combine efficacy data from …

… Treatment options are limited, and their efficacy in randomized … real-world effectiveness and
tolerability of SCLC treatments. … effectiveness of new and existing therapies (in the real world)…

… because it is the first conducted in real-world practice with a disease-free period of 22 months,
… [45], it is emphasized that the real-world efficacy of MOG might be underestimated due to …

… effectiveness of maintenance therapy and subsequent treatment lines as well as detailed
real-world … newer treatments that have proven efficacy, real-world elderly patients with MM live …

… was observed among ceritinib treated patients in the real world (median OS: 15.6 months) …
real world data as well as trial data that is being used to demonstrate the clinical effectiveness …