… live cell division dynamics in large spheroids that reproduce the cellular organization in
tumor micro-regions including cellular heterogeneity, and cell-cell and cell-microenvironment …

… This study paves the way for the investigation of molecular aspects and dynamic studies of
the … A tumor, or a tumor model such as a MCTS is not a population of exponentially growing …

… model using experimental measurements of cell cycle transition times, we show that the
model … to examine the cell cycle dynamics of individual cells within a growing population. The …

… dynamic biosystem rather than an unorganized cell mass. To test the hypothesis of related
key behaviour such as cell proliferation … of displaying several of the dynamic features of this …

… tumour spheroids are used as a culture model … tumour cell division dynamics in relation
with the 3D cell organization. To this aim we developed a 3D methodology and used spheroids …

… cell model, we analyze the experimental data that map the movement of cells in a fibrosarcoma
tumor spheroid … to the dynamics in confluent tissues in which cell division and apoptosis …

… -based mathematical model to describe the in vitro growth of tumour spheroids in response
… the average cell cycle length τ can generate in silico tumour spheroids with similar growth …

… and microenvironment-depending tumor model. … -2 spheroid suggests that pancreatic
cancer cell proliferation … results in activation of S cell cycle checkpoint and apoptosis […

… a recent mathematical model of avascular tumour spheroid growth which accounts for both
cell cycle dynamics and chemotactic driven cell movement. The model considers cells to exist …

… both cell cycle–independent and cell cycle–… our model of multicell tumor spheroids. Since
concentration profiles are computed during the time evolution of the whole cluster, the dynamic …