… cell dysfunction in cancer. Also, we discuss the relationship between T cell dysfunction and
cancer immunotherapy. … relationship between T cell dysfunction and cancer immunotherapy. …

… design and development of cancer therapies that target immune … of T cell dysfunction in
tumor microenvironments. In addition, we also discuss new immune checkpoint targets in cancer …

… of the T cell dysfunction gene scores, we … cell dysfunction and immunotherapy resistance
(Supplementary Table 4). We plotted the T cell dysfunction scores averaged across five cancer …

… A better understanding of intratumoral NK cell dysfunction should be of value from a … cell
dysfunction in the TME and the latest progress in research, and offer novel immunotherapeutic …

… and have proven critical for cancer immunotherapy. However, T cells are not as effective
against cancer as expected. This is partly because T cells enter a dysfunctional or exhausted …

… front, with a focus on T cells and implications in cancer immunotherapy. A combination of …
for the T cell dysfunction noted in obesity (Figure 1). The chronic stimulation T cells experience …

… immunotherapies to counteract the mechanisms of tumor-induced T-cell dysfunction to …
With the improved immunomonitoring of the novel cancer immunotherapies (see review by …

… , the value of novel technologies to dissect such dysfunction at the single cell level, and how
our emerging understanding of T cell dysfunction … Cancer immunotherapy comes of age. …

… In this Review, we discuss recent advances in the understanding of NK cell dysfunction
in tumors, as well as emerging strategies of NK-based checkpoint immunotherapy for tumors. …

… , including emerging interventions to prevent or reverse T-cell dysfunction developing ex …
T-cell dysfunction, emphasizes how it affects various types of T-cell immunotherapy approaches…