… and propose that DNA methylation turnover might facilitate key lineage decisions. … Our
model implies that DNAme turnover is important for cell fate decisions to occur, but it will be …

… With more advanced whole-genome sequencing studies unraveling regions of low CpG
densities as hot spots of dynamic DNA changes critical in cell fate decisions, our current …

… DNA methylation would be in development. Development can be seen as a series of
cellular fate restrictions and hence DNA methylation has … For example, neural stem cells (NSCs) …

… analysis of the effects of perturbing DNA methylation on mouse organogenesis at a whole
organism scale and affords new insights into the regulatory mechanisms of cell fate decisions. …

… activation that regulates plasticity of CD4 + T-cell cytokine expression. Here we show that …
cell effector and memory fate decisions. Whereas effector function of DNMT3a knockout T cells …

… demethylation to fundamental developmental processes such as cell fate specification, cell
… conserved role for TET proteins in cell fate determination associated with gastrulation and …

… DNA methylation changes play critical roles in the establishment of the impaired fate decision
… pathways governing intestinal cell fate decisions represent preferential targets for altered …

… The aim of the present review is to discuss the major advances concerning the DNA methylation
dynamics during cell fate commitment and differentiation processes during development…

… cell fate specification process is the mechanism by which cells make a choice, the so-called
cell fate decision… is binary 12 and steers cells to adopt one of two cell states, thus enabling …

… loss of DNA methylation that is … escape DNA methylation during its reestablishment. It remains
unresolved whether this early round of DNA demethylation is passive (ie, DNA methylation …