… We therefore next investigated whether early-life exposure to a … -life (GF/a)—exposure of
GF mice to a conventional microbiota abrogated the increased accumulation of iNKT cells in the …

… Because the hormone microenvironment exerts a significant effect on resident innate immune
cell function, endocrine disruption is likely to produce misregulated inflammation in tissues…

… highly heterogeneous cell types. In this review, we summarize the effect of early-life exposure
to … the effects on immune cell counts, baseline characteristics of cell-mediated and humoral …

… Persistent epigenetic effects of early-life exposure to EDCs: experimental and epidemiological
evidence Hormone signaling is known to induce dynamic changes in cellular function and …

… are likely mediators of later-life expression of early-life events. … -life diseases resulting from
early-life exposures in order to identify in utero and postnatal indicators of later-life diseases, …

… However, this can leave the neonate susceptible to bacterial or viral infections after birth
because neonatal T cell function is linked to a diminished production of the prototypic T H 1-type …

… Mice in the duration-of-life exposure condition and their controls were housed in cylindrical
transparent bakelite cages (fig. 2), hereafter referred to as gamma cages. The bedding was …

… intrauterine or early childhood exposure to arsenic also induces changes that will become
apparent much later in life. One epidemiological study indicated that exposure to arsenic in …

… Memory T cells are generated from exposure to antigen and … aspects of human T cells
function at distinct stages of life, from infancy through … relating to T cell function and persistence. …

… Accordingly, it is considered that developmental exposure to … in neurobehaviour and
reproductive function. Many chemicals … how exposure to environmental oestrogens during early …