Roles of activated Src and Stat3 signaling in melanoma tumor cell growth
G Niu, T Bowman, M Huang, S Shivers, D Reintgen… - Oncogene, 2002 - nature.com
… kinase inhibitors on Stat3 DNA-binding activity in melanoma cell lines. To … or Stat3 leads
to inhibition of melanoma cell growth and Bcl-x L and Mcl-1 expression. Because Src activity is …
to inhibition of melanoma cell growth and Bcl-x L and Mcl-1 expression. Because Src activity is …
Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth In vitro.
JR Grandis, SD Drenning… - The Journal of …, 1998 - Am Soc Clin Investig
… -binding activity of a Stat3-related protein in cells transformed … levels of STAT-binding activity
compared with benign lesions or … cancer cell lines demonstrate constitutively active Stat3 …
compared with benign lesions or … cancer cell lines demonstrate constitutively active Stat3 …
Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
… between the Pim and c-Myc activities in cell proliferation and lymphomagenesis, and
show a link between STAT3 and cell growth machinery (Figure 2). STAT3 and differentiation …
show a link between STAT3 and cell growth machinery (Figure 2). STAT3 and differentiation …
Modulation of gene expression and tumor cell growth by redox modification of STAT3
L Li, S Cheung, EL Evans, PE Shaw - Cancer research, 2010 - AACR
… STAT3 in coupling intracellular redox homeostasis to cell … To seek an effect of STAT3
oxidation on tumor cell growth, … with BC cell lines displaying constitutive STAT3 activity (14). …
oxidation on tumor cell growth, … with BC cell lines displaying constitutive STAT3 activity (14). …
Cell-to-cell adhesion modulates Stat3 activity in normal and breast carcinoma cells
A Vultur, J Cao, R Arulanandam, J Turkson, R Jove… - Oncogene, 2004 - nature.com
… an increased Stat3 activity in normal cells with cell-to-cell contact, under growth arrest
conditions… Given this association of Stat3 with cell proliferation, we predicted that cell growth arrest …
conditions… Given this association of Stat3 with cell proliferation, we predicted that cell growth arrest …
Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth
FM Corvinus, C Orth, R Moriggl, SA Tsareva, S Wagner… - Neoplasia, 2005 - Elsevier
… to constitutive STAT3 activity between CRC biopsies and colon cancer cell lines prompted us
to … Roles of activated Src and Stat3 signaling in melanoma tumor cell growth. Oncogene 21, …
to … Roles of activated Src and Stat3 signaling in melanoma tumor cell growth. Oncogene 21, …
[HTML][HTML] LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
B Fuh, M Sobo, L Cen, D Josiah, B Hutzen… - British journal of …, 2009 - nature.com
… both STAT3's transcription and DNA binding activities. Our results show that LLL-3 …
STAT3-specific DNA binding activity in U373 glioblastoma cells and MDA-MB-231 breast cancer …
STAT3-specific DNA binding activity in U373 glioblastoma cells and MDA-MB-231 breast cancer …
Therapeutically exploiting STAT3 activity in cancer—using tissue repair as a road map
… STAT3 activity fuels tumour growth by metabolic and other non-transcriptional mechanisms.
Here, we review the tumour-modulating activities of STAT3 … promotes cancer cell growth and …
Here, we review the tumour-modulating activities of STAT3 … promotes cancer cell growth and …
[HTML][HTML] Withaferin-A inhibits colon cancer cell growth by blocking STAT3 transcriptional activity
BY Choi, BW Kim - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
… colorectal cancer (HCT116) cells. And we evaluated the effects of withaferin-A on the
transcriptional activity of STAT3 and the growth of HCT116 cells in xenograft mouse tumor model. …
transcriptional activity of STAT3 and the growth of HCT116 cells in xenograft mouse tumor model. …
STAT3 mediates IL‐6‐induced growth inhibition in the human prostate cancer cell line LNCaP
MT Spiotto, TDK Chung - The Prostate, 2000 - Wiley Online Library
… cells with a STAT3 dominant-negative mutant. We show that IL-6 enhances, rather than inhibits,
cell growth when STAT3 … to the effect that STAT3 transcriptional activity plays a critical …
cell growth when STAT3 … to the effect that STAT3 transcriptional activity plays a critical …
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