Glial scar and immune cell involvement in tissue remodeling and repair following acute CNS injuries

C Raposo, M Schwartz - Glia, 2014 - Wiley Online Library
… The glial scar contributes to protection of the spared neural tissues by establishing a …
educating the immune cells to promote the healing of the CNS tissue. In turn, the immune cells, and …

The glial scar and central nervous system repair

JW Fawcett, RA Asher - Brain research bulletin, 1999 - Elsevier
… upregulation of glial fibrillary acidic protein (GFAP), which may extend for up to 1 cm from
the injury in rats 1, 50, but the cells that actually participate in the formation of the glial scar are …

[HTML][HTML] Spinal cord injury: From inflammation to glial scar

MB Leal-Filho - Surgical neurology international, 2011 - ncbi.nlm.nih.gov
Glial scar (GS) is the most important inhibitor factor to neuroregeneration after spinal cord
injury (SCI) and behaves as a tertiary lesion. The present review of the literature searched for …

Portrait of glial scar in neurological diseases

H Wang, G Song, H Chuang, C Chiu… - International journal …, 2018 - journals.sagepub.com
involved in glial scar formation in a coordinating manner. As for induction of reactive astrocytes
leading to glial scar … such as ependymal cells and NG2+ cells, are involved in gliogenesis …

New insights into glial scar formation after spinal cord injury

AP Tran, PM Warren, J Silver - Cell and tissue research, 2022 - Springer
… that emerging techniques reveal about both glia and non-glia in the context of scar formation.
We will additionally examine how wound and glial scar-associated products affect neurons…

The role of neural stem cells in regulating glial scar formation and repair

AM Nicaise, A D'Angelo, RB Ionescu, G Krzak… - Cell and Tissue …, 2022 - Springer
… the glial scar is imperative in the use of these cellsglial scar. Herein, we explore the current
work on endogenous and exogenous NSCs in the glial scar as well as the novel 3D stem cell

Glial scar—a promising target for improving outcomes after CNS injury

Y He, X Liu, Z Chen - Journal of Molecular Neuroscience, 2020 - Springer
… targeting on mediating glial scar formation are regarded as … molecules on glial scar, and the
process of glial scar formation … We hope to get a comprehensive understanding of glial scar

Beyond the glial scar: cellular and molecular mechanisms by which glial cells contribute to CNS regenerative failure

MT Fitch, J Silver - CNS regeneration, 1999 - Elsevier
… of the glial scar, and this chapter is dedicated to a discussion of the cellular as well as
molecular responses of oligodendrocytes, astrocytes, and microglial cells to traumatic injury and …

Deciphering glial scar after spinal cord injury

Y Zhang, S Yang, C Liu, X Han, X Gu, S Zhou - Burns & trauma, 2021 - academic.oup.com
… formation, and further analyse the contribution of these cells to scar formation. In … glial scar
components. Altogether, we aim to present a comprehensive decoding of the glial scar and …

Regeneration beyond the glial scar

J Silver, JH Miller - Nature reviews neuroscience, 2004 - nature.com
glial scar, which consists predominately of reactive astrocytes and proteoglycans. Axons
cannot regenerate beyond the glial scar… of the glial scar and the cellular and molecular …