Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines

A Müller, S Barat, X Chen, KC Bui… - International …, 2016 - spandidos-publications.com
… of human CC cell lines (TFK-1, SZ-1). in this study, we found that bromelain and papain have
… effect of bromelain was more effective compared to papain, ii) significant restriction of CC …

Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity

M Azarkan, E Maquoi, F Delbrassine, R Herman… - Scientific reports, 2020 - nature.com
bromelain, ananain and papain show a strong reduction of … bromelain and ananain had
a strong effect on the proliferation of the OCI-LY19 and HL-60 non-adherent cell lines, papain, …

Bromelain proteinases modulate the cd44 expression on human molt-4/8 leukemia and sk-mel-28 melanoma-cells in-vitro

T Harrach, F Gebauer, K Eckert… - International …, 1994 - spandidos-publications.com
… lymphoma cell line Namalwa… bromelain, chymotrypsin, papain, and trypsin on CD44s
expression on human Molt 4/8 lymphoma and SKMel 28 melanoma cells and found that bromelain

Bromelain proteases suppress growth, invasion and lung metastasis of B16F10 mouse melanoma cells

E Grabowska, K Eckert, I Fichtner… - International …, 1997 - spandidos-publications.com
bromelain, bromelain F9 and papain on B16F10 mouse melanoma cell lung colonization, in
vitro cell … growth were found on different tumor cell lines, including Lewis lung cancer cells (5,…

[PDF][PDF] Antiproliferative effect of bromelain like cysteine protease (PSA/BP-07) from Billbergia pyramidalis (Sims) Lindl. on human malignant cell lines–a preliminary …

DD Kadiri, PS Anand - Int J Pharma Bio Sci, 2016 - researchgate.net
bromelain like cysteine protease (PSA/BP07) from B. pyramidalis exerted its antiproliferative
activity on cancer cell lines. … , and enzyme mixture of bromelain and papain. Biotechnol. Adv. …

Cytotoxicity, Antibiotic Combination and Antiviral Activity of Papain Enzyme: In vitro study

SH Mohamed, WS Mohamed… - Asian Journal of …, 2020 - indianjournals.com
… Recently, we concluded that proteases enzymes such as bromelain and papain had …
liver cancer cell line hepG2 [33]. Also, MTT assays showed that papain at concentrations of …

Plant proteolytic enzyme papain abrogates angiogenic activation of human umbilical vein endothelial cells (HUVEC) in vitro

T Mohr, L Desser - BMC complementary and alternative medicine, 2013 - Springer
… It is known that cysteine proteases from plants, like bromelain and papain are capable to …
-angiogenic effects of papain on human umbilical vein endothelial cells (HUVEC) in vitro. …

Bromelain induces the differentiation of leukemic cells in vitro: an explanation for its cytostatic effects?

HR Maurer, M Hozumi, Y Honma… - Planta medica, 1988 - thieme-connect.com
… of Bromelain on this cell line. Bromelain also induced hemoglobin synthesis in K 562 cells in
… Interestingly, purified stem-Bromelain differs from other plant SH-proteases like papain and …

In vitro performance of free and encapsulated bromelain

JA Ataide, LC Cefali, MC Figueiredo, LEO Braga… - Scientific reports, 2021 - nature.com
… commercial bromelain in a panel of eight human tumor cell lines of different … cell line (Table
1, Fig. 3). Expressed as the concentration of bromelain required to inhibit 50% of cell

Antibacterial activity of papain and bromelain on Alicyclobacillus spp.

MM dos Anjos, AA da Silva, IC de Pascoli… - International journal of …, 2016 - Elsevier
… the enzymes papain and bromelain have an … papain was produced in Switzerland and the
bromelain in Indonesia. To evaluate the homogeneity of commercial papain and bromelain, …