… order of IC50s of mKRAS cell lines with a) all other cell lines and b) cell lines wild type for
all … cell lines which included seven of the 10 EGFR mutant cell lines, one cell line with EGFR …

… of EGFR in lrECM 3D cultured CRC cell lines, we hypothesized that these differences may
affect the sensitivity to EGFR kinase inhibition. To test our hypothesis, we treated CRC cells …

… cases of NSCLC accompanied by mutant EGFR, treatment targeting inhibition of EGFR
kinase activity in differentiated cancer cells may generate a population of cancer cells with stem …

… an EGFR inhibitor improves cisplatin sensitivity in oral squamous cell carcinoma (OSCC) cell
lines… The effects of a combination of AG1478, a specific EGFR tyrosine kinase inhibitor, with …

… cell lines for alterations in EGFR gene copy number, enhanced expression of EGFR and other
HER family members, and EGFR … NSCLC cell lines, we found that the presence of EGFR …

… cancer cells with EGFR inhibition even in cell lines that over-… (44%) ovarian cancer cell lines
express EGFR, a finding that … Over-expression of EGFR, was seen in three of four cell lines …

… Correlation between EGFR and cytotoxicity of EGFR inhibitors. As previously reported, the
11 EGFR inhibitors showed similar GI 50 fingerprints across the NCI60 cell line series (1). The …

… A549 cell line by chronic, repeated exposure to gefitinib. Compared with the A549 cells,
the A549/GR cells … the cross-resistance against other EGFR-TK inhibitors, including CL-387,758, …

… EGFR inhibitors from synthetic origin with their detailed synthetic methodology and brief
biological profile. EGFR inhibitors … NSCLC cell lines and found to be potent inhibitor of EGFR…

… that EGFR scores were predictive of sensitivity to EGFR inhibitors, Erlotinib and Gefitinib, and
a more general tyrosine kinase inhibitor (TKI), Sorafenib in lung cancer cell lines… that EGFR …