… We identified 35 trials evaluating surgery plus adjuvant chemotherapy versus surgery alone.
IPD were available for 26 of these trials and our analyses are based on 8447 participants (…

… Adjuvant chemotherapy (AC) plays now a significant role in the treatment of resected non-small
cell lung cancer (NSCLC) patients and has become standard in clinical practice. It took …

… In the 1980s and early 1990s, multiple studies of adjuvant chemotherapy in patients who
have undergone resection for NSCLC showed conflicting results. The Lung Cancer Study …

… In 1995, a meta-analysis reviewed eight cisplatin-based adjuvant chemotherapy trials that
… benefits of adjuvant chemotherapy for survival, we designed Adjuvant Lung Project Italy (…

… Adjuvant Lung Cancer Trial was designed to evaluate the effect of cisplatin-based
adjuvant chemotherapy on survival after complete resection of non–small-cell lung cancer. …

… A benefit from cisplatin-based adjuvant chemotherapy was … Big Lung Trial, no benefit from
adjuvant chemotherapy was … surgery followed by adjuvant chemotherapy with cisplatin and …

… lung cancer … lung cancer by giving adjuvant chemotherapy to patients with complete surgical
resection.This approach has been successful in patients with breast and colorectal cancer …

… was to determine whether preoperative or adjuvant chemotherapy improved disease-free …
5-year disease-free survival with preoperative or adjuvant chemotherapy (from 30% to 45%). …

… , esophageal, or non–small-cell lung cancer. These data led us to … tumor could predict
a survival benefit from cisplatin-based adjuvant chemotherapy in non–small-cell lung cancer…

… ) in favour of adjuvant chemotherapy. The effect was significant for adjuvant chemotherapy
in … In conclusion, our meta-analysis shows the efficacy of adjuvant chemotherapy in stages I …