New insights into small‐cell lung cancer development and therapy

Y Wang, S Zou, Z Zhao, P Liu, C Ke… - Cell Biology …, 2020 - Wiley Online Library
Lung cancer is often diagnosed at an advanced stage, rendering the disease intractable.
Lung cancer can be broadly categorized into non-small-cell … stage small-cell lung cancer (ED …

Mechanisms involved in lung cancer development in COPD

G Caramori, P Casolari, GN Cavallesco… - … of biochemistry & cell …, 2011 - Elsevier
lung cancer are tobacco smoking-related and (b) only a proportion of lifelong smokers will
develop COPD and/or squamous cell … smoking-related COPD and squamous cell carcinoma. …

[HTML][HTML] … immune cells and chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer

RM Bremnes, K Al-Shibli, T Donnem, R Sirera… - Journal of Thoracic …, 2011 - Elsevier
… This review covers the roles of immune cells in the tumor microenvironment in general and
in the non-small cell lung cancer (NSCLC) microenvironment in particular. The possibility of …

Suppression of retinoic acid receptor β in non-small-cell lung cancer in vivo: implications for lung cancer development

XC Xu, G Sozzi, JS Lee, JJ Lee… - … the National Cancer …, 1997 - academic.oup.com
… in some patients with non-small-cell lung cancer (NSCLC). These effects are … cell growth,
differentiation, or apoptosis (programmed cell death). When certain retinoid receptors in the cell

A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies

JR Kratz, J He, SK Van Den Eeden, ZH Zhu, W Gao… - The Lancet, 2012 - thelancet.com
… The frequent recurrence of early-stage non-small-cell lung cancer (NSCLC) is generally …
We aimed to develop and validate a practical, reliable assay that improves risk stratification …

Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways

AC Borczuk, L Gorenstein, KL Walter… - The American journal of …, 2003 - Elsevier
lung cancer histological cell type gene marker sets were associated with lung development
… in the two temporally associated lung development groups previously identified by self-…

4-year mortality in patients with non-small-cell lung cancer: development and validation of a prognostic index

F Blanchon, M Grivaux, B Asselain, FX Lebas… - The lancet …, 2006 - thelancet.com
… 80% of overall lung cancer cases … develop and validate a simple prognostic index for 4-year
mortality in patients with NSCLC by use of information obtained at the time of lung cancer

Non-small-cell lung cancer

C Gridelli, A Rossi, DP Carbone, J Guarize… - Nature reviews Disease …, 2015 - nature.com
… Although these data only deal with benefits before lung cancer development, smoking
cessation after diagnosis increases survival by months, which is an improvement on the outcomes …

Notch in lung development and lung cancer

BJ Collins, W Kleeberger, DW Ball - Seminars in cancer biology, 2004 - Elsevier
… in normal lung growth, especially in Clara cell precursors. Non-small cell lung cancers,
including … of the Notch pathway is a potential experimental approach to lung cancer treatment. …

[HTML][HTML] Targeted therapies in development for non-small cell lung cancer

T Reungwetwattana, GK Dy - Journal of carcinogenesis, 2013 - ncbi.nlm.nih.gov
… [4,5,6,7,8,9,10] Indeed, the changing landscape of lung cancer therapy was heralded … lung
cancer are summarized in Figure 1. This article delineates the rationale for the development