[HTML][HTML] The Dose/Fractionation Debate in Limited-Stage Small Cell Lung Cancer

K Du, X Liao, K Kishi - Cancers, 2024 - mdpi.com
… For the radical radiotherapy regimen recommended by current guidelines (45 Gy/30
fractions), we suggest moderately increasing the fractionation dose and total dose, which may …

… palliative radiotherapy (17 gy per two fractions) in advanced non–small-cell lung carcinoma is comparable to standard fractionation for symptom control and survival …

S Sundstrøm, R Bremnes, U Aasebø… - Journal of clinical …, 2004 - ascopubs.org
… whether our standard fractionation in Norway (42 Gy per 15 fractions) [… dose of 17 Gy; arm
B, 15 fractions of 2.8 Gy to a total dose of 42 Gy; and arm C, 25 fractions of 2 Gy to a total dose

Radiotherapy in limited small cell lung cancer: Fractionation and timing of modalities

AT Turrisi III, HR Withers - Seminars in Radiation Oncology, 1995 - Elsevier
… This article focuses on the issues of fractionation of the … treatment in small cell lung
cancer. Theoretical and clinical … tumor from cell wcle redistribution between dose fractions.I 1 …

Stereotactic hypofractionated radiation therapy for stage I non-small cell lung cancer

FB Zimmermann, H Geinitz, S Schill, A Grosu… - Lung cancer, 2005 - Elsevier
… such as classically termed tumordose fractionation, stereotactic single (high) dose RT was
… were also attempts to fractionate total tumor dose into several smaller fractions, still, however…

[HTML][HTML] High-dose and fractionation effects in stereotactic radiation therapy: Analysis of tumor control data from 2965 patients

I Shuryak, DJ Carlson, JM Brown, DJ Brenner - Radiotherapy and Oncology, 2015 - Elsevier
… We found 33 publications, which together contained data from 2965 patients, mostly treated
for early-stage non-small cell lung cancer (NSCLC) or brain metastases. We extracted data …

Radical accelerated radiotherapy for non-small cell lung cancer (NSCLC): a 5-year retrospective review of two dose fractionation schedules

SD Robinson, BA Tahir, KAR Absalom… - Radiotherapy and …, 2020 - Elsevier
… In this single-centre retrospective analysis, we compare both fractionation schemes for …
other common cancers. The majority of new lung cancer cases are non-small cell lung cancer (…

Precision hypofractionated radiation therapy in poor performing patients with non-small cell lung cancer: phase 1 dose escalation trial

KD Westover, BW Loo Jr, DE Gerber, P Iyengar… - International Journal of …, 2015 - Elsevier
… An MD Anderson phase 1 proton therapy trial with aims similar to this study evaluated
doses of 45, 52.5, and 60 Gy delivered in 15 fractions, but enrollment was limited to better-…

Dose-limiting toxicity after hypofractionated dose-escalated radiotherapy in non–small-cell lung cancer

DM Cannon, MP Mehta, JB Adkison… - Journal of clinical …, 2013 - ascopubs.org
… still limit dose-escalation strategies, even when a more fractionated approach is … doses in
commonly used SBRT fractionation schemes for central lung lesions (eg, 50 Gy in five fractions

Radiation Dose and Fractionation in Locally Advanced Lung Cancer: A Simple Question With a Complicated Answer

MJ Khandekar, FK Keane - JAMA oncology, 2021 - jamanetwork.com
… –small cell lung cancer, the optimal radiation dose and fractionation have been … doses lead
to improved tumor control, findings of a randomized phase 3 cooperative group trial of dose

[HTML][HTML] Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors

QT Le, BW Loo, A Ho, C Cotrutz, AC Koong… - Journal of Thoracic …, 2006 - Elsevier
cell lung cancer (NSCLC) or solitary metastases to the lung is … revised fractionation schedules
of 60 Gy in three fractions for … fractions or 50 Gy in five fractions for central tumors. These …