Definitive Radiotherapy in LocallyAdvanced Non-Small Cell Lung Cancer: Dose and Fractionation

N Dağoğlu, Ş Karaman, A Arifoğlu, S Küçücük… - Balkan Medical …, 2014 - dergipark.org.tr
dose escalation or shortening the total treatment time through conventional/altered fractionation,
… This review summarises the results of significant trials on dose and altered fractionation

Dose escalation, not “new biology,” can account for the efficacy of stereotactic body radiation therapy with non-small cell lung cancer

JM Brown, DJ Brenner, DJ Carlson - International journal of radiation …, 2013 - redjournal.org
… with either 1 fraction or 3-8 fractions. The reader is reminded that BED is a linear-quadratic
model-based estimate of equivalent biological dose that corrects for dose fractionation ( …

Modeling local control after hypofractionated stereotactic body radiation therapy for stage I non-small cell lung cancer: a report from the elekta collaborative lung …

N Ohri, M Werner-Wasik, IS Grills, J Belderbos… - International Journal of …, 2012 - Elsevier
… decrease with tumor size, we hypothesized that effective dose … a median of 3 fractions (range,
1-15 fractions) over a median … common fractionation schedules were 18 Gy in 3 fractions (n…

A phase I/II radiation dose escalation study with concurrent chemotherapy for patients with inoperable stages I to III non-small-cell lung cancer: phase I results of …

JD Bradley, J Moughan, MV Graham, R Byhardt… - International Journal of …, 2010 - Elsevier
… Our trial was initiated with a dose of 75.25 Gy in 2.15-Gy daily fractions (roughly 10%
lower than the MTD for 9311) because of concern about the additive toxicity of concurrent …

One versus three fractions of stereotactic body radiation therapy for peripheral stage I to II non-small cell lung cancer: a randomized, multi-institution, phase 2 trial

AK Singh, JA Gomez-Suescun, KL Stephans… - International Journal of …, 2019 - Elsevier
… The research nurse randomized patients by permuted block design by to 1 of 2 dose/fractionation
schemes (arms 1 or 2). The statistician determined the random allocation sequence …

Radiation Time, Dose, and Fractionation in the Treatment of Lung Cancer

D Gomez, MD Jeter, R Komaki, JD Cox - … Oncology in Lung Cancer, 2011 - Springer
… through the use of fractionation, that is, manipulating the time interval and dose of radiation
to … dose escalation with standard fractionation or hyperfractionation; large-dose fractionation

Long-term results of a phase III trial comparing once-daily radiotherapy with twice-daily radiotherapy in limited-stage small-cell lung cancer

SE Schild, JA Bonner, TG Shanahan, BJ Brooks… - International Journal of …, 2004 - Elsevier
fractions followed by a boost dose … -cell lung cancer. Patients were randomized to receive
either standard qd RT (60 Gy in 30 daily fractions) or split-course bid RT (30 Gy in 20 fractions

Accelerated hypofractionation for early-stage non-small-cell lung cancer

PCF Cheung, LTF Yeung, V Basrur, YC Ung… - International Journal of …, 2002 - Elsevier
… The dose fractionation of 48 Gy in 12 once-daily fractions used in our study can be completed
in an overall treatment time of 16 days, assuming that RT starts on a Monday. For patients …

… phase III CHARTWEL-trial (ARO 97-1) comparing hyperfractionated-accelerated versus conventionally fractionated radiotherapy in non-small cell lung cancer  …

M Baumann, T Herrmann, R Koch… - Radiotherapy and …, 2011 - Elsevier
… For early stage NSCLC, a dose-escalated schedule applying 2 fractions of 1.8 Gy per
day appears to be equally effective compared to surgery in matched-pair analysis [16]. …

Thoracic radiotherapy in small cell lung cancer: rationale for timing and fractionation

R Arriagada, JP Pignon, T Le Chevalier - Lung Cancer, 1989 - Elsevier
… To illustrate our reasoning we will use mean values on tumor control: if we assume for high
dose RT (over 50 Gy in classical fractionation) a probability of CR of 0.8 and a probability of …