GTV differentially impacts locoregional control of non-small cell lung cancer (NSCLC) after different fractionation schedules: subgroup analysis of the prospective …

M Soliman, A Yaromina, S Appold, D Zips… - Radiotherapy and …, 2013 - Elsevier
… an additional boost dose of 16 Gy to PTV2 (primary tumour and positive lymph nodes),
resulting in a total dose of 66 Gy in 33 fractions. For the CHARTWEL arm, a dose per fraction of …

… radiation therapy and 3-dimensional conformal radiotherapy for stage I non-small cell lung cancer: a pooled analysis of biological equivalent dose and local control

N Mehta, CR King, N Agazaryan, M Steinberg… - Practical radiation …, 2012 - Elsevier
… Given the variation in dose-fractionation, we revisited the issue of BED with respect to both
the LQ and USC models. Comparing BEDs between the LQ and USC models is important …

Dose-response in stereotactic irradiation of lung tumors

J Wulf, K Baier, G Mueller, MP Flentje - Radiotherapy and oncology, 2005 - Elsevier
… chemotherapy or altered fractionation has resulted in only … that doses of at least 70 Gy are
necessary in lung cancer and … fractionated series have been included in our dose response …

The impact of radiation on the tumor microenvironment: effect of dose and fractionation schedules

KM Arnold, NJ Flynn, A Raben… - Cancer growth and …, 2018 - journals.sagepub.com
tumor cell death between ablative and fractionated radiation could not be ruled out in this
study. In contrast, a study in TSA breast carcinoma … stage non–small-cell lung cancer (NSCLC). …

Stereotactic body radiation therapy for early-stage non–small-cell lung cancer: the pattern of failure is distant

JD Bradley, I El Naqa, RE Drzymala, M Trovo… - International Journal of …, 2010 - Elsevier
… peripheral lung cancers treated to 18 Gy × three fractions had excellent local control rates
with minimal toxicity. For central tumors, our dose fractionation scheme of 9 Gy × five fractions

Intra-patient variability of tumor volume and tumor motion during conventionally fractionated radiotherapy for locally advanced non-small-cell lung cancer: a …

G Bosmans, A van Baardwijk, A Dekker, M Öllers… - International Journal of …, 2006 - Elsevier
… no esophageal dose constraints. As the tumor dose was delivered in 1.8 Gy fractions, a …
twice a day (bid), with a minimum of 8 h between the 2 fractions, and given 5 days per week. …

Effect of thoracic radiotherapy timing and fractionation on survival in nonmetastatic small cell lung carcinoma

AT Wong, J Rineer, D Schwartz, D Becker, J Safdieh… - Clinical Lung Cancer, 2017 - Elsevier
… of nonmetastatic small cell lung cancer (SCLC). We analyzed the National Cancer Data Base
(NCDB… regarding the total radiation dose and the number of radiation fractions. The NCDB …

… radiation therapy dose is associated with improved survival in patients undergoing stereotactic body radiation therapy for stage I non–small-cell lung cancer

M Koshy, R Malik, RR Weichselbaum… - International Journal of …, 2015 - Elsevier
… study revealed a dose–survival relationship in patients with T2 lung cancer patients treated
… results and determine the optimal dose fractionation scheme as a function of tumor volume. …

Phase III trial comparing chemotherapy plus once-daily or twice-daily radiotherapy in stage III non-small-cell lung cancer

SE Schild, PJ Stella, SM Geyer, JA Bonner… - International Journal of …, 2002 - Elsevier
… of lung cancer and bid RT fractionation patterns for the treatment of head-and-neck … 20
fractions (1.5 Gy bid), for a total dose of 60 Gy in 40 fractions within 6 weeks. The EP doses were …

Different fractionation schemes tested by histological examination of autopsy specimens from lung cancer patients

HJ Eichhorn - The British Journal of Radiology, 1981 - academic.oup.com
fractions, which is still the method in common use. High-dose fractions should result in
considerable cell … during the longer intervals between fractions. A number of prospective studies …