Anti-vascular endothelial growth factor monoclonals in non-small cell lung cancer
AB Sandler, DH Johnson, RS Herbst - Clinical cancer research, 2004 - AACR
… prognostic factor, whether basic fibroblast growth factor is a favorable prognostic factor, and
whether other surrogate clinical markers, potentially released by damaged endothelial cells, …
whether other surrogate clinical markers, potentially released by damaged endothelial cells, …
Targeting the epidermal growth factor receptor in non-small cell lung cancer
RS Herbst, PA Bunn Jr - Clinical cancer research, 2003 - AACR
… The inhibition of tumor growth seen with EGFR-TK inhibition is also accompanied by … growth
factor (VEGF), basic fibroblast growth factor (bFGF), and TGF-α, all potent inducers of tumor …
factor (VEGF), basic fibroblast growth factor (bFGF), and TGF-α, all potent inducers of tumor …
Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancer
SS Sridhar, L Seymour, FA Shepherd - The lancet oncology, 2003 - thelancet.com
Despite aggressive surgical and chemotherapeutic interventions, non-small-cell lung cancer
(NSCLC) is the leading cause of cancer-related death in men and women with overall cure …
(NSCLC) is the leading cause of cancer-related death in men and women with overall cure …
Epidermal growth factor receptors in non-small cell lung cancer
D Veale, T Ashcroft, C Marsh, GJ Gibson… - … journal of cancer, 1987 - nature.com
… -,B and is the receptor for a class of tumour growth factors (TGF-ca). The clinical correlations
… small cell lung cancers (NSCLC). They were stained for epidermal growth factor receptor (…
… small cell lung cancers (NSCLC). They were stained for epidermal growth factor receptor (…
Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer
KJ O'Byrne, MI Koukourakis, A Giatromanolaki… - … journal of cancer, 2000 - nature.com
… In conclusion, VEGF and PD-ECGF are important angiogenic growth factors and have
prognostic significance in NSCLC. Furthermore the study underlines the prognostic significance of …
prognostic significance in NSCLC. Furthermore the study underlines the prognostic significance of …
Human squamous cell lung cancers express increased epidermal growth factor receptors.
FJ Hendler, BW Ozanne - The Journal of clinical …, 1984 - Am Soc Clin Investig
… , epidermal growth factor; EGF-R 1, a murine monoclonal epidermal growth factor receptor-…
The present study examined human lung cancer biopsy specimens for the presence of EGF …
The present study examined human lung cancer biopsy specimens for the presence of EGF …
Epidermal growth factor receptor mutations in small cell lung cancer
A Tatematsu, J Shimizu, Y Murakami, Y Horio… - Clinical Cancer …, 2008 - AACR
… It is well known that epidermal growth factor receptor (EGFR) … in some patients with small
cell lung cancers (SCLC). In this … The vast majority of epidermal growth factor receptor (EGFR) …
cell lung cancers (SCLC). In this … The vast majority of epidermal growth factor receptor (EGFR) …
Epidermal growth factor receptor expression in human lung cancer cell lines
M Haeder, M Rotsch, G Bepler, C Hennig, K Havemann… - Cancer research, 1988 - AACR
… Growth factor research and oncogene research are closely linked based on the hypothesis
of autocrine secretion; ie, cancer cells can produce and respond to their own growth factors (1…
of autocrine secretion; ie, cancer cells can produce and respond to their own growth factors (1…
Interleukin-8 stimulates cell proliferation in non-small cell lung cancer through epidermal growth factor receptor transactivation
F Luppi, AM Longo, WI De Boer, KF Rabe, PS Hiemstra - Lung cancer, 2007 - Elsevier
… non-small cell lung cancer cells, involving transactivation of the epidermal growth factor receptor
(… a central role in regulating cell proliferation and it has been therefore implicated in lung …
(… a central role in regulating cell proliferation and it has been therefore implicated in lung …
The Fibroblast Growth Factor Receptor Inhibitor PD173074 Blocks Small Cell Lung Cancer Growth In vitro and In vivo
OE Pardo, J Latigo, RE Jeffery, E Nye, R Poulsom… - Cancer research, 2009 - AACR
… in SCLC cells. Here, we show that the selective fibroblast growth factor receptor (FGFR)
inhibitor PD173074 blocks H-510 and H-69 SCLC proliferation and clonogenic growth in a dose-…
inhibitor PD173074 blocks H-510 and H-69 SCLC proliferation and clonogenic growth in a dose-…
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