Epigenetic mechanisms of chronic pain
… maintenance of chronic pain involve … cellular and molecular levels. Here, we focus on recent
studies that highlight the involvement of epigenetic mechanisms in the CNS in chronic pain …
studies that highlight the involvement of epigenetic mechanisms in the CNS in chronic pain …
Pain mechanisms in patients with chronic pain
D Fornasari - Clinical drug investigation, 2012 - Springer
… The mechanisms involved in the development of chronic pain are varied and complex. Pain
processes are plastic and unrelieved pain … structure involved in pain generation. Nociceptive …
processes are plastic and unrelieved pain … structure involved in pain generation. Nociceptive …
[HTML][HTML] Central nervous system targets: glial cell mechanisms in chronic pain
CR Donnelly, AS Andriessen, G Chen, K Wang… - …, 2020 - Elsevier
… pain pathogenesis. We also review two emerging areas in chronic pain research: 1) sexually
dimorphic glial cell … for potential pain therapeutics targeting glial cell mediators as well as …
dimorphic glial cell … for potential pain therapeutics targeting glial cell mediators as well as …
Chemokines in chronic pain: cellular and molecular mechanisms and therapeutic potential
… As chronic itch and chronic pain share some common mechanisms, we also discuss the
emerging roles of chemokines and chemokine receptors in chronic itch. Targeting specific …
emerging roles of chemokines and chemokine receptors in chronic itch. Targeting specific …
Mechanisms of pain modulation in chronic syndromes
H Bolay, MA Moskowitz - Neurology, 2002 - AAN Enterprises
… of inhibitory neurons due to apoptotic cell death. Recently, forebrain structures … mechanisms
of chronic pain may lead to more specific and effective treatment strategies for chronic pain…
of chronic pain may lead to more specific and effective treatment strategies for chronic pain…
Role of epigenetic mechanisms in chronic pain
D Mauceri - Cells, 2022 - mdpi.com
… , we will provide a brief overview of the mechanism by which miRNAs seem to influence
chronic pain. Sensitization of the pain pathways is brought forward by changes in the landscape …
chronic pain. Sensitization of the pain pathways is brought forward by changes in the landscape …
Perspectives in Pain Research 2014: Neuroinflammation and glial cell activation: The cause of transition from acute to chronic pain?
BE Cairns, L Arendt-Nielsen… - … Journal of Pain, 2015 - degruyter.com
… glial cell activations specifically in the dorsal root ganglion and spinal cord as a mechanism
possibly driving the transition to chronic pain. This has led to a focus on non-neuronal cells …
possibly driving the transition to chronic pain. This has led to a focus on non-neuronal cells …
Animal and cellular models of chronic pain
LX Wang, ZJ Wang - Advanced drug delivery reviews, 2003 - Elsevier
… systems for preclinical study of pain. This article reviews some of the most widely used or
promising new models for chronic pain. Partial spinal ligation, chronic constriction injury, and L5…
promising new models for chronic pain. Partial spinal ligation, chronic constriction injury, and L5…
Descending control mechanisms and chronic pain
QL Chen, MM Heinricher - Current rheumatology reports, 2019 - Springer
… The challenge will be to tease out mechanisms through which a particular behavioral … to
enhance or suppress pain, and to understand how these mechanisms contribute to chronic pain. …
enhance or suppress pain, and to understand how these mechanisms contribute to chronic pain. …
Commonalities between pain and memory mechanisms and their meaning for understanding chronic pain
… all contributed from the cell body, the neuron would need a mechanism in place to correctly
… after cellular stimulation, likely because their mRNAs are targets for signaling mechanisms to …
… after cellular stimulation, likely because their mRNAs are targets for signaling mechanisms to …
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