Akt: a double‐edged sword in cell proliferation and genome stability
N Xu, Y Lao, Y Zhang, DA Gillespie - Journal of oncology, 2012 - Wiley Online Library
… Addition of mitogens to quiescent (G0) mammalian cells rapidly triggers a number of
biochemical signalling cascades, including the PI3K/Akt pathway, to promote cell growth through …
biochemical signalling cascades, including the PI3K/Akt pathway, to promote cell growth through …
Low‐power laser irradiation promotes cell proliferation by activating PI3K/Akt pathway
L Zhang, D Xing, X Gao, S Wu - Journal of cellular physiology, 2009 - Wiley Online Library
… cell proliferation through PI3K/Akt signaling pathway. Akt serine/threonine protein kinases
are critical for the regulation of fundamental cellular processes including cell proliferation, …
are critical for the regulation of fundamental cellular processes including cell proliferation, …
Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
J Liang, JM Slingerland - Cell cycle, 2003 - Taylor & Francis
… PI3K pathway is protein kinase B (PKB), also known as Akt. … PI3K pathway including cell
proliferation, survival, and cellular … role of the PI3K/PKB (Akt) pathway in cell cycle progression. …
proliferation, survival, and cellular … role of the PI3K/PKB (Akt) pathway in cell cycle progression. …
G protein‐coupled receptor‐induced Akt activity in cellular proliferation and apoptosis
DC New, K Wu, AWS Kwok, YH Wong - The FEBS journal, 2007 - Wiley Online Library
… Akt pathways are also activated by a similar method of transactivation [25]. In Swiss 3T3 cells,
bradykinin and bombesin promote cellular proliferation … activates PI3K/Akt cascades [26]. A …
bradykinin and bombesin promote cellular proliferation … activates PI3K/Akt cascades [26]. A …
PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?
MA Lawlor, DR Alessi - Journal of cell science, 2001 - journals.biologists.com
… The serine/threonine protein kinase PKB (also known as Akt) … progression by stimulating
cell proliferation and inhibiting … pathway in Drosophila has been shown to markedly reduce …
cell proliferation and inhibiting … pathway in Drosophila has been shown to markedly reduce …
Palmitic acid inhibits prostate cancer cell proliferation and metastasis by suppressing the PI3K/Akt pathway
S Zhu, W Jiao, Y Xu, L Hou, H Li, J Shao, X Zhang… - Life Sciences, 2021 - Elsevier
… Since palmitic acid was demonstrated to inhibit prostate cancer cell proliferation, we next
examined whether it would affect cell cycle progression in PC3 and DU145 cells. The cells …
examined whether it would affect cell cycle progression in PC3 and DU145 cells. The cells …
ILK promotes cell proliferation in breast cancer cells by activating the PI3K/Akt pathway
Y Qu, C Hao, J Xu, Z Cheng… - Molecular Medicine …, 2017 - spandidos-publications.com
… demonstrated that ILK facilitated cell proliferation in breast cancer cells through activating
the PI3K/Akt pathway, suggesting a vital role of ILK in breast cancer cell growth. The present …
the PI3K/Akt pathway, suggesting a vital role of ILK in breast cancer cell growth. The present …
[PDF][PDF] Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1
ZJ Liu, M Xiao, K Balint, A Soma, CC Pinnix… - The FASEB …, 2006 - researchgate.net
… Similar effects were observed in HIAEC cells. Taken … pathway activation inhibits endothelial
cell proliferation by concurrently regulating both the MAPK and PI3K/Akt signaling pathways. …
cell proliferation by concurrently regulating both the MAPK and PI3K/Akt signaling pathways. …
… inhibits cell proliferation, promotes cell apoptosis, and induces cell cycle arrest via downregulating the PI3K/AKT/hTERT pathway in lung adenocarcinoma A549 cells
XX Lu, LY Cao, X Chen, J Xiao, Y Zou… - BioMed research …, 2016 - Wiley Online Library
… in various carcinoma models, we presumed that the PI3K/AKT pathway might be implicated
in the … AKT (p-AKT) were reduced and that cell proliferation was inhibited in A549 cells …
in the … AKT (p-AKT) were reduced and that cell proliferation was inhibited in A549 cells …
Acemannan accelerates cell proliferation and skin wound healing through AKT/mTOR signaling pathway
W Xing, W Guo, CH Zou, TT Fu, XY Li, M Zhu… - Journal of …, 2015 - Elsevier
… -induced cell proliferation and cyclin D1 … the AKT/mTOR signaling pathway To further
confirm that acemannan promoted cyclin D1 protein translation by AKT/mTOR signaling pathway, …
confirm that acemannan promoted cyclin D1 protein translation by AKT/mTOR signaling pathway, …
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