Clonal expansion of innate and adaptive lymphocytes
NM Adams, S Grassmann, JC Sun - Nature Reviews Immunology, 2020 - nature.com
… clonal expansion. This Review highlights the cellular processes that are required for clonal
expansion… between innate and adaptive lymphocytes, specifically NK cells and CD8 + T cells. …
expansion… between innate and adaptive lymphocytes, specifically NK cells and CD8 + T cells. …
T-cell repertoire diversity and clonal expansions in normal and clinical samples
C Pannetier, J Even, P Kourilsky - Immunology today, 1995 - cell.com
… of these clonal expansions is not yet well understood. … the clonal expansion of antigen-specific
T cells ]T helper cells in the … of resolution where the T-cell repertoire is described by some …
T cells ]T helper cells in the … of resolution where the T-cell repertoire is described by some …
Clonal expansion in non-cancer tissues
N Kakiuchi, S Ogawa - Nature Reviews Cancer, 2021 - nature.com
… Finally, we discuss the role of clonal expansion in normal tissues in … selected clones on
ageing, homeostatic regulation and the response to … Somatic mutations and clonal expansion …
ageing, homeostatic regulation and the response to … Somatic mutations and clonal expansion …
Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity
H Gudmundsdottir, AD Wells… - The Journal of Immunology, 1999 - journals.aai.org
… the dynamics of OVA-specific T cell clonal expansion in response to OVA peptide in vivo,
we … of donor T cells. As the rag-2 gene is required for recombination at Ag receptor loci, T …
we … of donor T cells. As the rag-2 gene is required for recombination at Ag receptor loci, T …
Somatic mutation and clonal expansion of B cells in an antigen‐driven immune response.
F Sablitzky, G Wildner, K Rajewsky - The EMBO journal, 1985 - embopress.org
… B cells in the course of which point mutations are introduced over many generations of clonal
growth … of this result forthe clonal expansion and selection of cells in the immune system we …
growth … of this result forthe clonal expansion and selection of cells in the immune system we …
… T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.
AD Wells, H Gudmundsdottir… - The Journal of clinical …, 1997 - Am Soc Clin Investig
… of activated T cells in clonal expansion, with TCR and CD28 signals having both overlapping
and differential effects on the induction and maintenance of T cell responses. (J. Clin. …
and differential effects on the induction and maintenance of T cell responses. (J. Clin. …
Single-cell repertoire analysis demonstrates that clonal expansion is a prominent feature of the B cell response in multiple sclerosis cerebrospinal fluid
GP Owens, AM Ritchie, MP Burgoon… - The Journal of …, 2003 - journals.aai.org
… Our goal was to evaluate the extent of B cell clonal expansion within the CNS of MS
patients. Consistent with previous analyses of the IgG H chain repertoire that identified …
patients. Consistent with previous analyses of the IgG H chain repertoire that identified …
Clonal expansion of T cells: a cytotoxic T-cell response in vivo that involves precursor cell proliferation.
F Denizot, A Wilson, F Battye… - Proceedings of the …, 1986 - National Acad Sciences
… studied were Ly-2- and nonspecific, and thus perhaps not T cells. We conclude that the
clonal selection model is applicable to at least one in vivo T-cell response. …
clonal selection model is applicable to at least one in vivo T-cell response. …
Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion
… of the activated population, indicating that our clonally expanded and activated cells are
indeed pathogen specific. We found some expanded nonactivated iNKT/MAIT TCR sequences, …
indeed pathogen specific. We found some expanded nonactivated iNKT/MAIT TCR sequences, …
Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2
… small clone sizes. Eleven IGHV genes were significantly enriched in expanded clones versus
non-expanded clones (… and viral epitope binding of B cells by using these germline IGHV. …
non-expanded clones (… and viral epitope binding of B cells by using these germline IGHV. …
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