Modeling cell signaling networks
NJ Eungdamrong, R Iyengar - Biology of the Cell, 2004 - Elsevier
… of signaling networks … cell signaling networks. Using heterotrimeric G protein pathways an
example, we demonstrate how interactions between two pathways can result in a network that …
example, we demonstrate how interactions between two pathways can result in a network that …
Logic-based models for the analysis of cell signaling networks
… to cell signaling in eukaryotes, the focus of this review, complex multicomponent networks …
We focus on logic-based models of biochemical signaling networks and refer the reader to the …
We focus on logic-based models of biochemical signaling networks and refer the reader to the …
A database for cell signaling networks
T Takai-Igarashi, Y Nadaoka… - Journal of Computational …, 1998 - liebertpub.com
… It is interesting to consider how cell-signaling networks have evolved, and we believe that
the comparative study of cell signaling networks between species is an important application …
the comparative study of cell signaling networks between species is an important application …
WNT signaling pathway and stem cell signaling network
M Katoh, M Katoh - Clinical cancer research, 2007 - AACR
… self-renewal of normal stem cells as well as proliferation or differentiation of progenitor (transit-amplifying)
cells. Breakage of the stem cell signaling network leads to carcinogenesis. …
cells. Breakage of the stem cell signaling network leads to carcinogenesis. …
Optimal prediction by cellular signaling networks
NB Becker, A Mugler, PR Ten Wolde - Physical review letters, 2015 - APS
… Living cells can enhance their fitness by anticipating environmental change. We study how
accurately linear signaling networks in cells can predict future signals. We find that maximal …
accurately linear signaling networks in cells can predict future signals. We find that maximal …
Modeling approaches for qualitative and semi-quantitative analysis of cellular signaling networks
R Samaga, S Klamt - Cell communication and signaling, 2013 - Springer
… formalisms for the description of cellular signaling networks that are of different complexity
(… graphs to cellular signaling networks such as the identification of signaling pathways and …
(… graphs to cellular signaling networks such as the identification of signaling pathways and …
Scalable simulation of cellular signaling networks
… the intra-cellular signalling networks triggered by extra-cellular stimuli (such as hormones
and growth factors). Such networks determine growth, differentiation, and other cell responses. …
and growth factors). Such networks determine growth, differentiation, and other cell responses. …
Spatial modeling of cell signaling networks
… affect the dynamics of the signaling microdomains. The predictions generated … signaling
network topology, biochemical kinetics, and spatial anisotropy in the regulation of the cellular …
network topology, biochemical kinetics, and spatial anisotropy in the regulation of the cellular …
Systematic calibration of a cell signaling network model
… One of the major difficulties in modeling cell signaling networks is the identification of the …
/feedforward connections commonly found in cell signaling pathways make the analysis difficult …
/feedforward connections commonly found in cell signaling pathways make the analysis difficult …
eXpression2Kinases (X2K) Web: linking expression signatures to upstream cell signaling networks
… the activity of cell signaling pathways is currently much more difficult. eXpression2Kinases
(X2K) computationally predicts involvement of upstream cell signaling pathways, given a …
(X2K) computationally predicts involvement of upstream cell signaling pathways, given a …