… Signaling networks have evolved to respond to distinct environmental stimuli with …
signaling enzymes in the cell, form a highly connected and perhaps irreducibly complex network …

… problem as one where the T cell signaling network must discriminate between two inputs:
infected APCs that present a small number of agonist ligands (a bona fide signal) in a sea of …

… These may involve a two-levelhierarchical approach wherein the overall signaling network
is modeled in termsof effective “circuit” or “algorithm” modules, and theneach module is …

… Cells … signaling networks that relay extracellular cues into the cell, culminating in the
reprogramming of various biochemical, genetic, and structural processes. The cellular signaling …

… into a unified cell signaling network. The longest path in the cell signaling network we have
… to the class I PI3K enzyme and further through class III PI3K to various cellular responses. …

… of signaling networks requires that we have an orderly approach if we are to understand what
these networks … Regulatory motifs in cell signaling networks. (A) A representative coherent …

… data into functional signaling networks in an attempt to better understand the host cell pathways
involved in the response to viral infection. A recent study used a network-based analysis …

… can be expanded to include other regulatory networks; for example, metabolic, gene … , how
can cell signaling networks be integrated into the larger networks of interacting cells, tissues, …

… Machine learning was applied for the automated derivation of causal influences in cellular
signaling networks. This derivation relied on the simultaneous measurement of multiple …

… cell apparatus involved in internal or external signal interpretation can be considered a
molecular network. … the signaling network resembles a type of neural network called a perceptron …