Methods for the analysis of protein phosphorylation–mediated cellular signaling networks
FM White, A Wolf-Yadlin - Annual Review of Analytical Chemistry, 2016 - annualreviews.org
… of signaling network function are daunting. The specific sites of phosphorylation within a
given cellular signaling network … response to different levels of cellular stimulation needs to be …
given cellular signaling network … response to different levels of cellular stimulation needs to be …
Cell signaling regulation by protein phosphorylation: a multivariate, heterogeneous, and context-dependent process
EK Day, NG Sosale, MJ Lazzara - Current opinion in biotechnology, 2016 - Elsevier
… phosphorylation-dependent signaling and from the tendency for some signaling processes
to occur heterogeneously among cells. … cell signaling regulation by protein phosphorylation. …
to occur heterogeneously among cells. … cell signaling regulation by protein phosphorylation. …
[HTML][HTML] The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy
F Ardito, M Giuliani, D Perrone… - International …, 2017 - spandidos-publications.com
… , since a single kinase or phosphatase may simultaneously have more substrates and
may function in various cell signaling pathways. One of the signaling pathways known for this …
may function in various cell signaling pathways. One of the signaling pathways known for this …
Protein phosphorylation in plant cell signaling
P Li, J Liu - Plant Phosphoproteomics: Methods and Protocols, 2021 - Springer
… -like protein kinases (RLKs) and receptor-like proteins (RLPs), and then transmitted to the
nucleus by complex cellular signaling networks, … of protein functions in plant cell signaling. …
nucleus by complex cellular signaling networks, … of protein functions in plant cell signaling. …
NetworKIN: a resource for exploring cellular phosphorylation networks
… Recent proteome-wide mapping of protein phosphorylation … for improved prediction of cellular
kinase–substrate relations. … insight into phosphorylation-modulated interaction networks. …
kinase–substrate relations. … insight into phosphorylation-modulated interaction networks. …
Network models of protein phosphorylation, acetylation, and ubiquitination connect metabolic and cell signaling pathways in lung cancer
… of lung cancer cells to TKIs. We highlight examples where cell signaling pathways involving
EGFR and ALK exhibit crosstalk with BioPlanet pathways: Transmembrane transport of …
EGFR and ALK exhibit crosstalk with BioPlanet pathways: Transmembrane transport of …
Integration of protein phosphorylation, acetylation, and methylation data sets to outline lung cancer signaling networks
… Our goal was to use large-scale mass spectrometry data to integrate cell signaling pathways
that involve protein phosphorylation, methylation, and acetylation. We hypothesized that …
that involve protein phosphorylation, methylation, and acetylation. We hypothesized that …
Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications
… Analysis of protein phosphorylation with flow cytometric techniques has emerged as a … of
cell signaling networks to understand cell function. Identification of signaling thresholds and …
cell signaling networks to understand cell function. Identification of signaling thresholds and …
A cell-signaling network temporally resolves specific versus promiscuous phosphorylation
E Kanshin, LP Bergeron-Sandoval, SS Isik, P Thibault… - Cell reports, 2015 - cell.com
… It is generally viewed that signaling networks have evolved so that kinase- or phosphatase-…
Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase …
Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase …
Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways
L Coussens, PJ Parker, L Rhee, TL Yang-Feng… - Science, 1986 - science.org
… To obtain evolutionary clues to this question and to verify the existence of protein kinase
C-related sequences in other species, we isolated human protein kinase C cDNA clones from a …
C-related sequences in other species, we isolated human protein kinase C cDNA clones from a …
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