过去一年中添加的文章,按日期排序

The deubiquitinase OTUD1 deubiquitinates TIPE2 and plays a protective role in sepsis-induced lung injury by targeting TAK1-mediated MAPK and NF-κB signaling

T Ming, H Liu, M Yuan, J Tian, Q Fang, Y Liu… - Biochemical …, 2024 - Elsevier
2 天前 - kinase (MAPK) and nuclear factor kappa-B (NF-κB) signaling pathways in the
present study. Subsequently, we probed the molecular … mitogen-activated protein kinase

[HTML][HTML] The effect and mechanism of Patchouli alcohol on cognitive dysfunction in AD mice induced by Aβ1-42 oligomers through AMPK/mTOR pathway

LT Lin, ST Zhang, BL Shang, YQ Dai, XQ Cheng… - Brain Research …, 2024 - Elsevier
2 天前 - … -activated protein kinase)/mTOR (Mammaliam target of rapamycin) signaling
pathway. … analysis of the corresponding signaling pathways and inflammatory changes through …

mTORC2: A neglected player in aging regulation

W Xu, H Chen, H Xiao - Journal of Cellular Physiology - Wiley Online Library
2 天前 - … ) regulates signaling networks associated with cellular senescence. mTORC2
regulates most downstream age-related signals by phosphorylating the key kinase protein kinase

Dual PI3K/mTOR Inhibitor BEZ235 combined with BMS-1166 Promoting Apoptosis in Colorectal Cancer

X Liu, W Xu, L Li, Z Zhang, M Lu, X Xia - International Journal of Medical …, 2024 - medsci.org
2 天前 - … to PD-1, restores T cell function, and enhances tumor immune … cellular signaling
pathways may also lead to cellular transformation. In this study, the SW480 and SW480R cell

Network pharmacology analysis of the regulatory effects and mechanisms of ALAE on sow reproduction in vivo and in vitro

L Zhao, J Zhang, J He, M Guo, H Wu, X Ma, Z Yu… - Journal of …, 2024 - Elsevier
2 天前 - … GO analysis revealed the enhancement of biological processes including negative
regulation of apoptosis and protein phosphorylation. Cellular components including plasma …

Enterovirus 3C Cleavage of RIPK3 Dysregulates Inflammatory Signaling and Drives Rapid Evolution in Primates

CM Rezanka - 2024 - escholarship.org
3 天前 - … response, inflammatory signaling pathways are known to be … Receptor interacting
protein kinase 3 (RIPK3) is a key … , a highly inflammatory and lytic cell death pathway. During …

Intracellular Signaling Pathways Involved in the Regulation of Gene Expression by Pilocarpine

H Sakazume, T Morita, H Yamaguchi… - Journal of Oral Biosciences, 2024 - Elsevier
3 天前 - … use on gene expression mediated by mitogen-activated protein kinase (MAPK)
activity. … cell line that is derived from salivary duct. HSY cell line is often used in cell signaling

High ambient temperature may induce presbyopia via TRPV1 activation

Y Nakazawa, Y Kuno, H Shimada, N Nagai… - Medical Molecular …, 2024 - Springer
3 天前 - … We conducted experiments using cultured human lens epithelial cell lines under …
activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) and p38 pathways, …

Xiaoke Bitong capsule alleviates inflammatory impairment via inhibition of the TNF signaling pathway to against diabetic peripheral neuropathy

L Tian, M Yang, S Tu, K Chang, H Jiang, Y Jiang… - Phytomedicine, 2024 - Elsevier
3 天前 - … Seventy-one active compositions of XBC and five potential targets, including
mitogen-activated protein kinase 8 (MAPK), interleukin-6 (IL-6), poly-ADP-ribose polymerase-1 (…

[HTML][HTML] … extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

S Bobis-Wozowicz, M Paw, M Sarna… - … and Signaling: CCS, 2024 - ncbi.nlm.nih.gov
3 天前 - … pro-survival pathways regulated by intracellular kinases such as protein kinase
B (PKB, … and mitogen-activated protein kinases (MAPK), including extracellular signal-regulated …