Emerging role of protein-protein transnitrosylation in cell signaling pathways

T Nakamura, SA Lipton - Antioxidants & redox signaling, 2013 - liebertpub.com
… regulate SNO signaling pathways. Below, we describe recent findings on protein-protein
transnitrosylation reactions that affect cell signaling pathways in both health and disease. …

Bacterial cupredoxin azurin hijacks cellular signaling networks: proteinprotein interactions and cancer therapy

M Gao, J Zhou, Z Su, Y Huang - Protein Science, 2017 - Wiley Online Library
… to interfere in different cellular signaling pathways. So far, two segments have been identified
responsible for interactions between azurin and the signaling targets. The central segment …

Differential proteinprotein interactions of LRRK 1 and LRRK 2 indicate roles in distinct cellular signaling pathways

L Reyniers, MG Del Giudice, L Civiero… - Journal of …, 2014 - Wiley Online Library
… the LRRK2 signaling network. In order to better understand the relationship between cellular
signaling functions of LRRK1 and LRRK2, we have screened for proteinprotein interaction …

Modeling cell signaling networks

NJ Eungdamrong, R Iyengar - Biology of the Cell, 2004 - Elsevier
… to understanding cell signaling networks. Using heterotrimeric G protein pathways an …
physiology, coupled with emerging high throughput techniques for detecting protein-protein

[HTML][HTML] Identification of protein interactions involved in cellular signaling

J Westermarck, J Ivaska, GL Corthals - Molecular & Cellular Proteomics, 2013 - ASBMB
… principles of cellular regulation and provides a detailed account of approaches required to
comprehensively map signaling protein-protein interactions in any particular cellular system …

Oncogenic re-wiring of cellular signaling pathways

T Pawson, N Warner - Oncogene, 2007 - nature.com
… In a similar fashion, proteins expressed as a consequence of oncogenic fusions, mutations
or amplifications can elicit ectopic proteinprotein interactions that re-wire signaling pathways

Single-Molecule Study of ProteinProtein Interaction Dynamics in a Cell Signaling System

X Tan, P Nalbant, A Toutchkine, D Hu… - The Journal of …, 2004 - ACS Publications
… To study protein interactions in cell signaling, ensemble measurements, which … of cell
signaling often involve only a few molecules and then are magnified along the signaling pathways. …

Information theory in systems biology. Part II: proteinprotein interaction and signaling networks

Z Mousavian, J Díaz, A Masoudi-Nejad - … in cell & developmental biology, 2016 - Elsevier
… The cellular signaling network responds to the input gradient signals, detected by the
gradient sensing system, by means of an output indicating the direction of cell movement. The …

Engineering cell signaling modulators from native proteinprotein interactions

W Zhang, M Ben-David, SS Sidhu - Current opinion in structural biology, 2017 - Elsevier
… have revolutionized our understanding of aberrant signaling networks in human diseases. A
strategy … on engineering natural proteinprotein interactions for modulation of cell signaling. …

Resolving the network of cell signaling pathways using the evolving yeast two-hybrid system

V Ratushny, EA Golemis - Biotechniques, 2008 - Taylor & Francis
… understanding of protein-protein interactions, which have allowed us to define cellular
machines. … intended to map genome-scale protein-protein interactions for model organisms and …