Protein‐protein interaction detection: methods and analysis
VS Rao, K Srinivas, GN Sujini… - International journal of …, 2014 - Wiley Online Library
… transduction pathways. Recent developments have also led to the construction … networks
having all the protein-protein interactions using computational methods for signaling pathways …
having all the protein-protein interactions using computational methods for signaling pathways …
Cell‐to‐cell and type‐to‐type heterogeneity of signaling networks: insights from the crowd
…, Single Cell Signaling in Breast Cancer … - Molecular systems …, 2021 - embopress.org
… Further, we encouraged participants to incorporate external data and resources of prior
knowledge, such as pathways and protein–protein interaction databases, in their models. …
knowledge, such as pathways and protein–protein interaction databases, in their models. …
Tissue-specific alternative splicing remodels protein-protein interaction networks
… These proteins participate in significantly more interactions in protein-protein interaction (PPI)
networks than other proteins. Using LUMIER, an automated PPI assay, we observe that …
networks than other proteins. Using LUMIER, an automated PPI assay, we observe that …
Protein–protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
A Virkamäki, K Ueki, CR Kahn - The Journal of clinical …, 1999 - Am Soc Clin Investig
… although the insulin signaling network is complex, modern cell biology and biochemistry are
… the insulin signal transduction pathways into an understanding of how these pathways can …
… the insulin signal transduction pathways into an understanding of how these pathways can …
The membrane environment can promote or suppress bistability in cell signaling networks
… , increased concentration promotes bistability through enhanced protein–protein binding,
while lower mobility and membrane-enhanced spatiotemporal correlations suppress bistability. …
while lower mobility and membrane-enhanced spatiotemporal correlations suppress bistability. …
Dissecting the specificity of protein-protein interaction in bacterial two-component signaling: orphans and crosstalks
… In this study, we dissect the specificity of protein-protein interactions governing two-component
signaling (TCS… wiring diagram towards a system-level understanding of cellular signaling. …
signaling (TCS… wiring diagram towards a system-level understanding of cellular signaling. …
[HTML][HTML] Heat shock proteins in cell signaling and cancer
BJ Lang, TL Prince, Y Okusha, H Bunch… - … (BBA)-Molecular Cell …, 2022 - Elsevier
… Many cell signaling events are mediated by the chemical … in cell signaling events with a focus
on oncogenic signaling. We also … cell signaling events that may link PTMs with the cellular …
on oncogenic signaling. We also … cell signaling events that may link PTMs with the cellular …
Techniques for the analysis of protein-protein interactions in vivo
S Xing, N Wallmeroth, KW Berendzen… - Plant physiology, 2016 - academic.oup.com
… and catabolism, almost all cellular functions depend on and are executed by complex
protein-protein interactions (PPIs). While complete biochemical pathways and even some protein …
protein-protein interactions (PPIs). While complete biochemical pathways and even some protein …
Human cancer protein-protein interaction network: a structural perspective
… related human protein-protein interfaces and the topological properties of the cancer network.
… of six interaction networks: 1) the human protein-protein interaction network, (PIN), 2) the …
… of six interaction networks: 1) the human protein-protein interaction network, (PIN), 2) the …
Identifying functional modules in protein–protein interaction networks: an integrated exact approach
MT Dittrich, GW Klau, A Rosenwald, T Dandekar… - …, 2008 - academic.oup.com
… Motivation: With the exponential growth of expression and protein–protein interaction (PPI) …
in PPI networks, sharing common cellular function beyond the scope of classical pathways, …
in PPI networks, sharing common cellular function beyond the scope of classical pathways, …