Differentiation, survival, and function of embryonic stem cell–derived endothelial cells for ischemic heart disease
Z Li, JC Wu, AY Sheikh, D Kraft, F Cao, X Xie, M Patel… - Circulation, 2007 - Am Heart Assoc
… In summary, stem cell therapy is an exciting area of investigation. With further validation,
the Flk + /VE-cadherin + isolated ESC-ECs described here could provide a continual source of …
the Flk + /VE-cadherin + isolated ESC-ECs described here could provide a continual source of …
Mechanisms of cell death in heart disease
K Konstantinidis, RS Whelan… - … , thrombosis, and vascular …, 2012 - Am Heart Assoc
… aimed at inhibiting cell death may provide novel therapies for these common and lethal … to
cell death during myocardial infarction and heart failure in the section on heart disease below. …
cell death during myocardial infarction and heart failure in the section on heart disease below. …
Tissue engineering therapy for cardiovascular disease
HM Nugent, ER Edelman - Circulation research, 2003 - Am Heart Assoc
… Heart valve replacement by mechanical or biological valve … common treatment for advanced
valvular heart disease. The major … cells, there has also been substantial work on therapies to …
valvular heart disease. The major … cells, there has also been substantial work on therapies to …
Cell therapy of peripheral arterial disease: from experimental findings to clinical trials
Z Raval, DW Losordo - Circulation research, 2013 - Am Heart Assoc
… The first major clinical trial of stem cell therapy in peripheral vascular disease was the
Therapeutic Angiogenesis using Cell Transplantation study, demonstrating safety and providing …
Therapeutic Angiogenesis using Cell Transplantation study, demonstrating safety and providing …
Gene therapy for refractory angina and cell therapy for heart failure: experience of a Brazilian research group
RT Sant'Anna, B Eibel, MM Markoski, CG Rodrigues… - Gene therapy, 2020 - nature.com
… Taken as a whole, our results with gene therapy approaches for heart diseases showed that
… Regarding cell therapy for cardiovascular diseases, our results in preclinical and clinical …
… Regarding cell therapy for cardiovascular diseases, our results in preclinical and clinical …
Stem cell therapy for ischemic heart disease: beginning or end of the road?
C Stamm, A Liebold, G Steinhoff… - Cell …, 2006 - journals.sagepub.com
… of patients with ischemic heart disease. Clinical efficacy data are … heart function in cell-treated
patients. This review is an attempt to describe the scientific basis for cardiac cell therapy …
patients. This review is an attempt to describe the scientific basis for cardiac cell therapy …
Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction
M Jain, H DerSimonian, DA Brenner, S Ngoy, P Teller… - Circulation, 2001 - Am Heart Assoc
… animals receiving myoblast cell therapy (MI+cell). In vivo and ex vivo cardiac physiology and
myoblast cell survival were studied at 3 and 6 weeks after cell therapy. Cell grafts were also …
myoblast cell survival were studied at 3 and 6 weeks after cell therapy. Cell grafts were also …
The Challenge for Stem Cell Therapy: Overview of the Problem: Heart Attack and Heart Failure
MS Penn, EJ Topol - Stem Cells and Myocardial Regeneration, 2007 - Springer
… Ischemic heart disease remains the leading cause of chronic heart failure (CHF). The
prevalence of CHF has increased dramatically over the last three decades, with more than 10% of …
prevalence of CHF has increased dramatically over the last three decades, with more than 10% of …
Clinical applications of stem cells for the heart
KC Wollert, H Drexler - Circulation research, 2005 - Am Heart Assoc
… cell therapy may be feasible in patients. The overall clinical experience also suggests that
stem cell therapy can be safely performed, if the right cell … severe ischemic heart disease, it …
stem cell therapy can be safely performed, if the right cell … severe ischemic heart disease, it …
Molecular mechanisms for cardiovascular stem cell apoptosis and growth in the hearts with atherosclerotic coronary disease and ischemic heart failure
YJ GENG - Annals of the New York Academy of Sciences, 2003 - Wiley Online Library
… heart failure who desperately need heart transplantation. A major challenge to stem cell
therapy is that transplanted stem cells … microenvironment in the infarcted heart. In addition to …
therapy is that transplanted stem cells … microenvironment in the infarcted heart. In addition to …