Glucocorticoid receptor variants: clinical implications

RH DeRijk, M Schaaf, ER De Kloet - The Journal of steroid biochemistry …, 2002 - Elsevier
… The clinical implication is that the regulation of the HPA-axis should be envisioned as a …
Probably, cell-type, cell-state and the specific antibody used will all influence the outcome. …

Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting

ES Antonarakis, AJ Armstrong, SM Dehm… - Prostate cancer and …, 2016 - nature.com
… AR splice variants (AR-Vs). In this review, we will discuss evolving insights into AR-V
expression in prostate cancers and their implications in contemporary prostate cancer clinical care, …

[HTML][HTML] Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19

CI van der Made, MG Netea, FL van der Veerdonk… - Genome medicine, 2022 - Springer
variants that are associated with severe forms of COVID-19. We focus on rare genetic variants
… proportion of cases with critical COVID-19 and discuss the potential clinical implications. …

Tall cell variant of papillary thyroid carcinoma without extrathyroid extension: biologic behavior and clinical implications

RA Ghossein, R Leboeuf, KN Patel, M Rivera, N Katabi… - Thyroid, 2007 - liebertpub.com
Background: The tall cell variant (TCV) is a histologic subtype of papillary thyroid carcinoma
(PTC) that is more aggressive than “classical” PTC. Most authors believe that TCV's worse …

[HTML][HTML] Variant histology in bladder cancer: diagnostic and clinical implications

AJ Black, PC Black - Translational cancer research, 2020 - ncbi.nlm.nih.gov
… The objective of this review is to highlight the important diagnostic, prognostic and therapeutic
implications of the most commonly encountered variant histologies in bladder cancer. For …

Clinical implications of cytogenetic variants in chronic myelocytic leukemia (CML)

J Whang-Peng, GP Canellos, PP Carbone, JH Tjio - Blood, 1968 - ashpublications.org
Serial cytogenetic studies were performed on 179 chronic myelocytic leukemia patients (CML)
at the Clinical Center of the National Institutes of Health. Patients were divided into 6 …

[HTML][HTML] Emerging SARS-CoV-2 variants: genetic variability and clinical implications

A Dubey, S Choudhary, P Kumar, S Tomar - Current microbiology, 2022 - Springer
… substitution protects the variants from both humoral and HLA-restricted cellular immunity, …
T-cell responses was observed for this variant and the vast majority of CD8 + T-cell epitopes …

[HTML][HTML] Basal cell carcinoma: biology, morphology and clinical implications

AN Crowson - Modern pathology, 2006 - Elsevier
… pathologist is referring to and also that the diagnosis has a specific clinical implication. In
summation, in our hands ‘metatypical' and ‘basosquamous' carcinoma are used synonymously. …

Cellular effects and clinical implications of SLC2A3 copy number variation

GC Ziegler, P Almos, RV McNeill… - Journal of Cellular …, 2020 - Wiley Online Library
clinical fields. We will then portray the potential impact of structural SLC2A3 variation on clinical
… determine the effects of structural SLC2A3 variation, and propose hypotheses regarding …

Clinical implications of HIV-1 minority variants

JZ Li, DR Kuritzkes - Clinical infectious diseases, 2013 - academic.oup.com
Clinicians should be aware of the novel technologies that are moving into routine clinical
use and the clinical implications of HIV-1 minority variants. Additional studies are needed to …