22 天前 - The serotonin pathway has long been proposed as a promising target for pulmonary
arterial hypertension (PAH)—a progressive and uncurable disease. We developed a …

35 天前 - … of genetic predispositions and cellular signaling pathways, … By bridging the gap
between basic science discoveries … but show ongoing ventricular remodeling, along with …

35 天前 - … remodeling in rats with acute myocardial infarction induced heart failure and to explore
the possible mechanism, so as to provide a basis … fiber type and cell cross-sectional area…

37 天前 - … Understanding the cellular and molecular basis of heart damage at cell type-specific
level in different types of hypertension is crucial for developing targeted therapies. In this …

57 天前 - … , which provides a scaffold for the cellular constituents of the heart and, furthermore,
… remodeling, fibrosis still remains elusive in CKD. A recent study in this issue of JACC: Basic …

73 天前 - … Wnt signaling pathway is a key pathway to regulate cell … Myocardial remodeling
leads to decreased left ventricular … in AMI can provide a new basis for the treatment of AMI. In …

87 天前 - … Here, in nonischemic human HF, we describe a mouse model of HF and a cellular
model of ANGII-induced remodeling and upregulation of MCU which is consistent with a …

87 天前 - … device treatment exerted, at least in part, its beneficial effects on cardiopulmonary
remodeling and RV function in PAH by modulating immune cell activation and inflammation. …

140 天前 - … the structural basis of trans-scar … remodeling of ventricles, where fibrotic scars
alter APP differently as the excitation frequency varies, but the role of this structural remodeling …

162 天前 - … the role of fibrotic remodeling in arrhythmogenesis involves … coupling may represent
a cell culture artifact and its … pathophysiologic relevance and molecular basis of fibroblast-…