The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond
C Conforti-Andreoni, P Ricciardi-Castagnoli… - Cellular & molecular …, 2011 - nature.com
Nucleotide-binding oligomerization domain (NOD)-containing protein-like receptors (NLRs)
are a recently discovered class of innate immune receptors that play a crucial role in …
are a recently discovered class of innate immune receptors that play a crucial role in …
Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases
N Kubben, T Misteli - Nature Reviews Molecular Cell Biology, 2017 - nature.com
… in cell and molecular mechanisms that are common between human premature ageing
diseases … characterized premature ageing diseases and exhibits a wide range of cellular, tissue …
diseases … characterized premature ageing diseases and exhibits a wide range of cellular, tissue …
Microbes in gastrointestinal health and disease
AS Neish - Gastroenterology, 2009 - Elsevier
… , deployed, and optimized complex immune mechanisms that monitor and control this
microbial ecosystem. These cellular mechanisms have homeostatic roles beyond the traditional …
microbial ecosystem. These cellular mechanisms have homeostatic roles beyond the traditional …
Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease
BS Van der Veen, MPJ de Winther… - Antioxidants & redox …, 2009 - liebertpub.com
… in cell signaling and cell–cell … diseases. In this article, our knowledge pertaining to the
biologic role of MPO and its downstream effects and mechanisms of action in health and disease …
biologic role of MPO and its downstream effects and mechanisms of action in health and disease …
Polyphenols and human health: prevention of disease and mechanisms of action
… The interaction of polyphenols with cellular signaling pathways involved in chronic disease.
… The interaction of polyphenols with cellular signaling pathways involved in chronic disease. …
… The interaction of polyphenols with cellular signaling pathways involved in chronic disease. …
Inflammasomes and their roles in health and disease
M Lamkanfi, VM Dixit - Annual review of cell and developmental …, 2012 - annualreviews.org
Inflammasomes are a set of intracellular protein complexes that enable autocatalytic
activation of inflammatory caspases, which drive host and immune responses by releasing …
activation of inflammatory caspases, which drive host and immune responses by releasing …
Pulmonary immune cells in health and disease: polymorphonuclear neutrophils
Y Sibille, FX Marchandise - European Respiratory Journal, 1993 - Eur Respiratory Soc
… Among the mechanisms implicated in the removal of PMNs, apoptosis or programmed cell
death appears to play a central role. Apoptosis is characterized by morphological changes, …
death appears to play a central role. Apoptosis is characterized by morphological changes, …
Reactive nitrogen species: molecular mechanisms and potential significance in health and disease
MC Martinez, R Andriantsitohaina - Antioxidants & redox signaling, 2009 - liebertpub.com
… RNS, highlighting the potential cellular targets and the expected cell effects. Next, we give …
living cell, and finally, we look at the consequences of RNS in health, including diseases such …
living cell, and finally, we look at the consequences of RNS in health, including diseases such …
Inflammasomes in health and disease
… downregulation either through secreted factors or cell–cell interactions. Examples of these
… In summary, the host has evolved distinct mechanisms to regulate inflammasome activation …
… In summary, the host has evolved distinct mechanisms to regulate inflammasome activation …
Iron transport & homeostasis mechanisms: their role in health & disease
SS Nadadur, K Srirama, A Mudipalli - Indian Journal of Medical …, 2008 - journals.lww.com
… A comprehensive discussion on metal transport and homeostasis mechanisms and their
role in health and disease is beyond the scope of this review article. To have a focused …
role in health and disease is beyond the scope of this review article. To have a focused …