Red blood cell homeostasis: mechanisms and effects of microvesicle generation in health and disease
JKF Leal, MJW Adjobo-Hermans… - Frontiers in physiology, 2018 - frontiersin.org
Red blood cells (RBCs) generate microvesicles to remove damaged cell constituents such
as oxidized hemoglobin and damaged membrane constituents, and thereby prolong their …
as oxidized hemoglobin and damaged membrane constituents, and thereby prolong their …
Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism
Y Zhang, H Xu - Current molecular medicine, 2007 - ingentaconnect.com
… We will review current knowledge of the secretases (-, -, and secretases) involved in APP
processing and various molecular and cellular mechanisms underlying intracellular trafficking …
processing and various molecular and cellular mechanisms underlying intracellular trafficking …
Roles and mechanisms of exosomal non-coding RNAs in human health and diseases
C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
… diseases. In this review, we comprehensively discuss the underlying regulatory mechanisms
of exosomes in human diseases… health and diseases, including cancers, metabolic diseases…
of exosomes in human diseases… health and diseases, including cancers, metabolic diseases…
Skeletal muscle in health and disease
J Morgan, T Partridge - Disease models & mechanisms, 2020 - journals.biologists.com
… of the cellular mechanisms that govern the growth and regeneration of skeletal muscle,
and highlight the defects in satellite cell function that give rise to muscular dystrophies. …
and highlight the defects in satellite cell function that give rise to muscular dystrophies. …
Roles of PPARs in health and disease
… LDL, a critical event in foam cell formation. A feed-forward mechanism has been proposed
whereby oxidized fatty acids that enter the cell through oxidized LDL can activate PPARγ, …
whereby oxidized fatty acids that enter the cell through oxidized LDL can activate PPARγ, …
Role of caveolae and caveolins in health and disease
AW Cohen, R Hnasko, W Schubert… - Physiological …, 2004 - journals.physiology.org
… the mechanisms by which caveolae and caveolins participate in human disease processes.
… may exploit caveolar potocytosis as a mechanism for cellular invasion. In the same auspice, …
… may exploit caveolar potocytosis as a mechanism for cellular invasion. In the same auspice, …
Cellular mechanisms of resistance to chronic oxidative stress
Y Sagara, R Dargusch, D Chambers, J Davis… - Free Radical Biology …, 1998 - Elsevier
… and, ultimately, apoptotic cell death. Several HT-22 subclones that are 10-fold resistant to
exogenous glutamate were isolated and the mechanisms involved in resistance characterized. …
exogenous glutamate were isolated and the mechanisms involved in resistance characterized. …
Reactive oxygen species in health and disease
AA Alfadda, RM Sallam - BioMed research international, 2012 - Wiley Online Library
… , and cellular mechanisms involved in mediating the ROS actions offer promising venues as
they propose novel potential therapeutic agents for the ROS-linked diseases. Few examples …
they propose novel potential therapeutic agents for the ROS-linked diseases. Few examples …
Endothelial dysfunction as a cellular mechanism for vascular failure
T Hirase, K Node - American Journal of Physiology-Heart …, 2012 - journals.physiology.org
… Accordingly, the endothelial dysfunction that is induced by atherogenic stimuli is considered
to play crucial roles as a cellular mechanism in the development of vascular failure. …
to play crucial roles as a cellular mechanism in the development of vascular failure. …
Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications
R Weiskirchen, S Weiskirchen, F Tacke - Molecular aspects of medicine, 2019 - Elsevier
… or Gli1 positive mesenchymal stem cell-like cells, to a transition of various cell types into …
principles of fibrogenic molecular signals and cellular mechanisms in various organs - such …
principles of fibrogenic molecular signals and cellular mechanisms in various organs - such …