The unfolded protein response and cellular senescence. A review in the theme: cellular mechanisms of endoplasmic reticulum stress signaling in health and disease

O Pluquet, A Pourtier… - … of Physiology-Cell …, 2015 - journals.physiology.org
… It results in ER homeostasis restoration or in cell death. Senescence is a complex cell phenotype
… It is mainly characterized by a cell enlargement, a permanent cell-cycle arrest, and the …

Selectivity of pharmacological tools: implications for use in cell physiology. A review in the theme: cell signaling: proteins, pathways and mechanisms

MC Michel, R Seifert - American Journal of Physiology-Cell …, 2015 - journals.physiology.org
… This article reviews the concept of inhibitor selectivity and its implication for cell physiology.
… of inhibitor potency and differences in potency between cell-free systems and intact cells. …

Cellular and molecular processes in ovarian cancer metastasis. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis

TL Yeung, CS Leung, KP Yip… - … of Physiology-Cell …, 2015 - journals.physiology.org
… A clear understanding of these cellular and molecular mechanisms will definitely shed
light … In this review we discuss the possible mechanisms by which ovarian cancer cells …

Cellular and Molecular Mechanisms of Single and Collective Cell Migrations in Drosophila: Themes and Variations

SM Pocha, DJ Montell - Annual review of genetics, 2014 - annualreviews.org
… we explore the themes and variations of individual and collective cellreview how genetic
studies in Drosophila have advanced our understanding of cellular and molecular mechanisms

Targeting Wnt signaling in colorectal cancer. A review in the theme: cell signaling: proteins, pathways and mechanisms

L Novellasdemunt, P Antas… - … of Physiology-Cell …, 2015 - journals.physiology.org
… Here we discuss the Wnt-activating mechanisms in CRC and review the current advances …
In this review, we discuss the canonical Wnt signaling pathway and its activating mechanisms

Molecular and cellular themes in inflammation and immunology

CS Herrington, PA Hall - The Journal of Pathology: A Journal of …, 2008 - Wiley Online Library
… knowledge of the cellular and molecular mechanisms of fibrosis… review by Appay and Sauce
21 considers the mechanisms … inflammatory and immunological mechanisms are applicable …

STIM and Orai proteins as novel targets for cancer therapy. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis

A Vashisht, M Trebak… - … of Physiology-Cell …, 2015 - journals.physiology.org
cellular functions including hallmarks of cancer development such as cell cycle progression
and cellular … In this review, we will retrospect the data supporting a key role for STIM1, STIM2…

Hypoxia: a key player in antitumor immune response. A review in the theme: cellular responses to hypoxia

MZ Noman, M Hasmim, Y Messai… - … of Physiology-Cell …, 2015 - journals.physiology.org
cellular stromal components, extracellular matrix fibers, cytokines, and other metabolic mediators
are also involved. In this review … detrimental to antitumor effector cell functions. We also …

The primary cilium as sensor of fluid flow: new building blocks to the model. A review in the theme: cell signaling: proteins, pathways and mechanisms

HA Praetorius - American Journal of Physiology-Cell …, 2015 - journals.physiology.org
… many epithelial cell types over the years. Nevertheless, part of the central mechanism of signal
… The current review considers the recent advances that allow us to fill some of the holes in …

Hypoxia-inducible factors in T lymphocyte differentiation and function. A review in the theme: cellular responses to hypoxia

JH Tao, J Barbi, F Pan - … Journal of Physiology-Cell …, 2015 - journals.physiology.org
… these regulatory mechanisms influence the processes of T cell differentiation, cell survival
… In reviewing the many and diverse roles played by HIF-1 in T cell biology we aim to highlight …