Metabolic regulation of antibiotic resistance
JL Martínez, F Rojo - FEMS microbiology reviews, 2011 - academic.oup.com
… Furthermore, mutations on some of the genes coding for proteins involved in the cellular
metabolism, such as rafDI (encoding ADP-l-glycero-d-mannose-6-epimerase) or gapA (…
metabolism, such as rafDI (encoding ADP-l-glycero-d-mannose-6-epimerase) or gapA (…
The role of antibiotics and antibiotic resistance in nature
RI Aminov - Environmental microbiology, 2009 - Wiley Online Library
… The horizontal gene transfer step may be not necessary if the cellular metabolic
mechanisms affected have a sufficiently broad specificity to cope with novel substrates such as …
mechanisms affected have a sufficiently broad specificity to cope with novel substrates such as …
Bacterial metabolism and antibiotic efficacy
… As such, perturbations to bacterial metabolic homeostasis are significant consequences of
… antibiotic efficacy in the context of bacterial metabolism: (1) antibiotics alter the metabolic …
… antibiotic efficacy in the context of bacterial metabolism: (1) antibiotics alter the metabolic …
Metabolic constraints on the evolution of antibiotic resistance
… A large body of evidence exists on mutations that confer antibiotic resistance, but we know
only relatively little about how such mutations affect cellular metabolism, either directly or …
only relatively little about how such mutations affect cellular metabolism, either directly or …
Environmental free radicals efficiently inhibit the conjugative transfer of antibiotic resistance by altering cellular metabolism and plasmid transfer
H Li, R Song, Y Wang, R Zhong, T Wang, H Jia, L Zhu - Water Research, 2022 - Elsevier
… Antibiotic resistant bacteria (ARB) can be conferred by antibiotic resistance genes (ARGs), …
withstand the antibacterial or bactericidal effects of antibiotics (Woodford and Ellington, 2007; …
withstand the antibacterial or bactericidal effects of antibiotics (Woodford and Ellington, 2007; …
Antibiotic resistance: current perspectives
A Petchiappan, D Chatterji - ACS omega, 2017 - ACS Publications
… (46) Genome and metabolome data of several clinical isolates of pathogenic strains have
shed more light on mechanisms of antibiotic resistance and revealed new cellular pathways as …
shed more light on mechanisms of antibiotic resistance and revealed new cellular pathways as …
Bacterial enzymes and antibiotic resistance
AM Egorov, MM Ulyashova… - Acta Naturae …, 2018 - cyberleninka.ru
… targets, enzymatic modification of intracellular targets, enzymatic transformation of
antibiotics, and the implementation of cellular metabolism reactions. The main mechanisms of …
antibiotics, and the implementation of cellular metabolism reactions. The main mechanisms of …
Clinically relevant mutations in core metabolic genes confer antibiotic resistance
… in cellular metabolism, in which the diverse array of metabolic … to elucidate metabolic
aspects of antibiotic resistance. … to detect mutations in metabolism-related genes. Constant …
aspects of antibiotic resistance. … to detect mutations in metabolism-related genes. Constant …
Compensation of the metabolic costs of antibiotic resistance by physiological adaptation in Escherichia coli
N Händel, JM Schuurmans, S Brul… - Antimicrobial agents …, 2013 - Am Soc Microbiol
… metabolic consequences of antibiotic resistance, the genomic and transcriptomic profiles of
an amoxicillin-resistant … in cell wall maintenance, DNA metabolic processes, cellular stress …
an amoxicillin-resistant … in cell wall maintenance, DNA metabolic processes, cellular stress …
Metabolic fitness landscapes predict the evolution of antibiotic resistance
… A central, yet unsolved question is how resistance evolution affects cell growth … resistance
mutants from their effects on cell metabolism. The model maps metabolic effects of resistance …
mutants from their effects on cell metabolism. The model maps metabolic effects of resistance …
相关搜索
- antibiotic resistance genes
- evolution of antibiotic resistance
- antibiotic resistance determinants
- antibiotic resistance metabolic costs
- antibiotic resistance bacterial metabolism
- antibiotic resistance metabolic regulation
- nonheritable antibiotic resistance
- acquisition of antibiotic resistance
- antibiotic resistance genome scale metabolic models
- antibiotic resistance in nature
- challenge of antibiotic resistance
- conjugative transfer of antibiotic resistance
- antibiotic resistance in microbes
- antibiotic resistance reservoir
- antibiotic resistance mechanisms
- antibiotic resistance metabolic constraints