Cellular responses to endoplasmic reticulum stress and apoptosis

VI Rasheva, PM Domingos - Apoptosis, 2009 - Springer
… protein response (UPR), have evolved to detect the accumulation of misfolded proteins in the
ER and activate a cellular response … In certain severe situations of ER stress, however, the …

Cellular response to endoplasmic reticulum stress: a matter of life or death

M Boyce, J Yuan - Cell Death & Differentiation, 2006 - nature.com
… as the ER stress response (ESR). Normally, this suite of responses succeeds in restoring
ER homeostasis. However, in metazoans, persistent or intense ER stress can also trigger …

Endoplasmic reticulum stress responses

M Schröder - Cellular and molecular life sciences, 2008 - Springer
In homeostasis, cellular processes are in a dynamic equilibrium. Perturbation of homeostasis
causes stress. In this review I summarize how perturbation of three major functions of the …

Endoplasmic reticulum stress responses in plants

SH Howell - Annual review of plant biology, 2013 - annualreviews.org
… Che P, Howell SH, 2007; An endoplasmic reticulum stress response in Arabidopsis is mediated
by proteolytic processing and nuclear relocation of a membrane-associated transcription …

From endoplasmic-reticulum stress to the inflammatory response

K Zhang, RJ Kaufman - Nature, 2008 - nature.com
… Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic
inflammatory response. Cell 124, 587–599 (2006). This study identifies CREBH, an ER-stress-inducible …

[HTML][HTML] Roles of endoplasmic reticulum stress in immune responses

JS So - Molecules and cells, 2018 - Elsevier
… function to resolve ER stress and dysfunction. This … response (UPR) and is an adaptive
cellular response that elicits specific intracellular signaling pathways to protect against ER stress (…

Cell death induced by endoplasmic reticulum stress

R Iurlaro, C Muñoz‐Pinedo - The FEBS journal, 2016 - Wiley Online Library
… Many conditions that impose stress on cells, including hypoxia, starvation, infections and …
cell and promote endoplasmic reticulum stress. The cellular response involves the activation of …

[HTML][HTML] Endoplasmic reticulum stress: cell life and death decisions

C Xu, B Bailly-Maitre, JC Reed - The Journal of clinical …, 2005 - Am Soc Clin Investig
Disturbances in the normal functions of the ER lead to an evolutionarily conserved cell
stress response, the unfolded protein response, which is aimed initially at compensating for …

Endoplasmic reticulum stress response and neurodegeneration

W Paschen, T Mengesdorf - Cell calcium, 2005 - Elsevier
… To restore ER functioning, specific stress responses are activated one of which is the unfolded
protein response (UPR). UPR is characterized by a shutdown of global protein synthesis …

Regulation of translational initiation during cellular responses to stress

CO Brostrom, MA Brostrom - Progress in nucleic acid research and …, 1997 - Elsevier
… This review deals with an emerging literature that relates protein chaperones associated
with cellular stress response systems to the coordinate regulation of translational initiation and …