… We briefly discuss brain aging in general, then … cellular senescence in neurodegenerative
diseases. Finally, we discuss the observations for heavy metals inducing cellular senescence. …

… the cells to divide again, even though senescent cells can … Cell senescence is observed
in cells derived from embryonic … brain cells are damaged by AD, and this causes the brain …

… irreversible growth arrest is cellular senescence, a stress response … cellular senescence
is primarily involved in normal development, cell plasticity, and tissue repair, when the cellular …

… , induction into cell senescence promotes an immunogenic program which facilitates
immune clearance of these damaged cells. Under physiological conditions, senescent cells can …

… Here we discuss the data indicating how cellular senescence affects … therapies targeting
senescent cell populations in MS. … and human brain, comprising 5–10 % of all CNS cells and a …

… The plasticity of worker longevity has led to the hypothesis that senescence is not a simple
… of cellular senescence in the brain of foragers, nurses, and diutinus bees. The brain was …

… Because the cellular senescence process accelerates ageing and promotes ageing-associated
brain disorders, senescence could be a potential therapeutic target for …

… Cellular senescence, which is characterized by an irreversible cell-cycle arrest 1 accompanied
… astrocytes and microglia that accumulate in the brains of MAPT P301S PS19 mice can be …

… However, senescent cells accumulate in various tissues … the causal roles of cellular senescence
in diseases of aging and to … and in various regions of the brain with natural aging,78, 79, …

… role in brain aging, a process known as cellular senescence. Cellular senescence has either
… The most salient characteristic of senescence is an irreversible withdrawal from the cell …