… present cellular senescence as the ultimate driver of the aging process, as a “causal nexus”
… , which we term the “causal nexus”, is in fact cellular senescence. The subcellular damage …

… targeting senescent … a causal role of cellular senescence in the development of NAFLD in
rodents and humans. We will elaborate on key cellular and molecular features of senescence …

… Therefore, the present review discusses the emerging interrelationship of oxi-inflammatory
stress, cellular senescence and immunosenescence as the causal nexus of aging and …

… senescent cells or inhibitors of the senescence-associated secretory phenotype (SASP).
Furthermore, we highlight the evidence that cellular senescence … role of cellular senescence in …

… Cellular senescence, the non-dividing altered state into … of cell division (subsequently
termed cellular senescence) … , these studies implicate senescent cells as a major nexus for …

… shown that the process of cellular senescence, a tumor suppressive … of senescent cells
and describe the impact of these factors on tissue homeostasis. We also summarize the cellular …

… Here, we discuss one such factor, cellular senescence, its role as a cellular response to stress
and … Cellular senescence suppresses cancer Cellular senescence generally refers to the …

… These cause cell cycle arrest, which is a feature of senescent cells (16). When growth arrest
… multiple cell divisions, the senescence is known as Cell senescence (CS) is at the nexus …

… at the nexus of many redox reactions, loss of which induces cellular senescence (Figure 2). …
between metabolism, cell signaling, and cell fates, particularly cellular senescence, which …

… cell populations and the prevention of cellular senescence. We also consider how stress-induced
senescence, … As autophagy is at the nexus of protein homeostasis, organelle turnover, …