The molecular intersection between senescence and major depression in the elderly
BS Diniz - The American Journal of Geriatric Psychiatry, 2018 - Elsevier
… —and cellular senescence in general—… cellular and molecular senescence and the
enhanced clinical aging phenotype observed in LLD? Are these molecular and cellular senescent …
enhanced clinical aging phenotype observed in LLD? Are these molecular and cellular senescent …
Oxidative stress-induced cellular senescence: is labile iron the connecting link?
L Nousis, P Kanavaros, A Barbouti - Antioxidants, 2023 - mdpi.com
… ROS, but evidence concerning cellular senescence is sparse. In the present review article,
we discuss aspects of oxidative stress-induced cellular senescence, with special attention to …
we discuss aspects of oxidative stress-induced cellular senescence, with special attention to …
The Achilles' heel of cancer survivors: fundamentals of accelerated cellular senescence
S Shafqat, EA Chicas, A Shafqat… - The Journal of Clinical …, 2022 - Am Soc Clin Investig
… over other mechanisms assumes that senescence drives accelerated aging processes in …
our Review on cellular senescence and advocate that considering cellular senescence as the …
our Review on cellular senescence and advocate that considering cellular senescence as the …
Cellular senescence at the crossroads of inflammation and Alzheimer's disease
A Guerrero, B De Strooper… - Trends in …, 2021 - cell.com
… The question arises whether senescence-induced inflammation … of cellular senescence
as a driver of the aging phenotype, and discuss the current evidence that connects senescence …
as a driver of the aging phenotype, and discuss the current evidence that connects senescence …
Mechanisms and regulation of cellular senescence
L Roger, F Tomas, V Gire - International journal of molecular sciences, 2021 - mdpi.com
… The hallmarks of cellular senescence include: prolonged cell … , known as the
senescence-associated secretory phenotype (… Replicative senescence was the first cellular …
senescence-associated secretory phenotype (… Replicative senescence was the first cellular …
Role of cellular senescence in type II diabetes
A Narasimhan, RR Flores, PD Robbins… - …, 2021 - academic.oup.com
… diabetes promote cellular senescence. Diabetes-induced cellular senescence contributes to
… Thus, type II diabetes is both a cause and consequence of cellular senescence. This review …
… Thus, type II diabetes is both a cause and consequence of cellular senescence. This review …
Theories and mechanism of aging and longevity through evolutionary lens: a coalition of plant anti-oxidants
… Hayflick first described the phenomenon of cellular senescence in the 1960s. According to
Hayflick, cellular senescence is the result of the shortening of telomeres, cellular dysfunction. …
Hayflick, cellular senescence is the result of the shortening of telomeres, cellular dysfunction. …
[HTML][HTML] Towards prevention of aneuploidy-associated cellular senescence and aging: more questions than answers?
M Kirsch-Volders, M Fenech - Mutation Research/Reviews in Mutation …, 2023 - Elsevier
… causal mechanism. Naina Bhatia-Dey et al. considered cellular senescence as the ultimate
driver, the causal nexus, of … on the contribution of cellular senescence and epigenetics to the …
driver, the causal nexus, of … on the contribution of cellular senescence and epigenetics to the …
Evolutionary genetic bases of longevity and senescence
DR Govindaraju - Longevity genes: a blueprint for aging, 2015 - Springer
… In accordance with the Darwinian (multilevel) and developmental model, the aging process
is initiated, in principle, shortly after the formation of zygote ((ie, cellular senescence followed …
is initiated, in principle, shortly after the formation of zygote ((ie, cellular senescence followed …
[PDF][PDF] Aging is programmed, selected for, and adaptive. 23. The eco-evolutionary flow of information in the causation of aging
K Heininger - researchgate.net
… All 10 significantly enriched loci contained genes linked to either inflammation or cellular
senescence pathways, and SNPs near regulators of senescence were particularly associated …
senescence pathways, and SNPs near regulators of senescence were particularly associated …