… actually play a causative role in developmental defects (Fig. 1). … of senescence can contribute
to disease, and highlight how the study of senescence in additional developmental defects …

… We discuss how a primary role of cellular senescence is to contribute to normal development,
cell … Finally, it is worth mentioning that the link between senescence and congenital defects …

… , senescence and aging are distinguishable processes (92). Indeed, cellular senescence
occurs … In this context, the immune clearance is defective and senescent cells are not removed, …

… role of senescence during embryo development and … cellular senescence. In addition,
given the extraordinary relevance of embryogenesis for the organism and the impact that defects …

… cellular senescence as a trigger of tissue remodelling that acts during normal embryonic
development … , an impaired senescent programme results in morphological defects in the adult. …

… defects. Here, we review the three primary cell senescence programs described so far (replicative,
stress-induced, and developmentally programmed senescence), their onset during …

… Cellular senescence, a permanent state of cell cycle arrest … In physiological conditions,
senescent cells can be removed … However, as we age, senescent cells accumulate in tissues, …

… cellular senescence with a special focus on their translational relevance and suitability for
identifying and characterizing senescent cells in … Defective mitophagy leads to accumulation of …

… Surprisingly, developmental senescence is not … developmental defects [56]. Other mechanisms,
such as apoptosis, may partially compensate for the loss of developmental senescence …

… during senescence of Zeb1 mutant MEFs. Instead, there is ectopic expression of two other
cell … of diminished progenitor cell proliferation and developmental defects in Zeb1-null mice. …