Living on a break: cellular senescence as a DNA-damage response
F D'adda Di Fagagna - Nature Reviews Cancer, 2008 - nature.com
… Oncogene activation also causes DDR activation and cellular senescence. Oncogene-… for
the involvement of the DDR in the control of cellular senescence. The DNA-damage response …
the involvement of the DDR in the control of cellular senescence. The DNA-damage response …
Cell senescence, DNA damage, and metabolism
R Shmulevich, V Krizhanovsky - Antioxidants & Redox Signaling, 2021 - liebertpub.com
… Recent Advances: Cellular metabolism plays a … cell senescence. In the past decade, our
knowledge about the interplay between cell signaling, cell metabolism, and cellular senescence …
knowledge about the interplay between cell signaling, cell metabolism, and cellular senescence …
Human cell senescence as a DNA damage response
T Von Zglinicki, G Saretzki, J Ladhoff… - Mechanisms of ageing …, 2005 - Elsevier
… of senescence that are not induced by either DNA damage or … of SDFs is a marker for cellular
senescence. This immediately … cellular senescence, both within in vitro and in vivo settings. …
senescence. This immediately … cellular senescence, both within in vitro and in vivo settings. …
DNA damage, cellular senescence and organismal ageing: causal or correlative?
JH Chen, CN Hales, SE Ozanne - Nucleic acids research, 2007 - academic.oup.com
… stress and attenuate DNA damage contribute towards longevity. … oxidative damage levels of
macromolecules including DNA … role of DNA damage in cellular senescence and organismal …
macromolecules including DNA … role of DNA damage in cellular senescence and organismal …
Cellular senescence and DNA repair
Z Lou, J Chen - Experimental cell research, 2006 - Elsevier
… that cellular senescence could be triggered by DNA damage. In … DNA damage response
pathway. This review will discuss the link between DNA repair defects and cellular senescence. …
pathway. This review will discuss the link between DNA repair defects and cellular senescence. …
Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer
G Sulli, R Di Micco, FA di Fagagna - Nature Reviews Cancer, 2012 - nature.com
… factors in the context of cellular senescence that is induced by … DNA damage
checkpoint-induced cell cycle arrest and the persistent cell cycle arrest that is typical of cellular …
checkpoint-induced cell cycle arrest and the persistent cell cycle arrest that is typical of cellular …
DNA damage response and cellular senescence in tissues of aging mice
… independent, DNA damage-induced senescence increases with … with the idea that cellular
senescence might be among the … DNA damage is a major factor to cause cellular senescence …
senescence might be among the … DNA damage is a major factor to cause cellular senescence …
DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?
… results in less telomeric damage and slower telomere shortening, … and telomeric DNA
damage during cellular senescence. … and telomeric DNA damage driving cellular senescence. …
damage during cellular senescence. … and telomeric DNA damage driving cellular senescence. …
The DNA damage signaling pathway connects oncogenic stress to cellular senescence
FA Mallette, G Ferbeyre - Cell cycle, 2007 - Taylor & Francis
… Several forms of DNA damage can be easily detected in cells as foci that accumulate …
the DNA damage foci found in senescent cells ODDI (oncogene‑induced DNA damage foci)…
the DNA damage foci found in senescent cells ODDI (oncogene‑induced DNA damage foci)…
[HTML][HTML] Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes
K Nagai, T Matsushita, T Matsuzaki, K Takayama… - Osteoarthritis and …, 2015 - Elsevier
… DNA damage and telomere dysfunction resulted in subsequent DNA damage responses and
eventual cellular senescence… through which SIRT6 promotes DNA repair and protects from …
eventual cellular senescence… through which SIRT6 promotes DNA repair and protects from …
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