… cellular senescence of the brain and discuss recent studies, which have shown that elimination
of senescent cells can lead to alleviation of brain … senescent brain cells may lead to brain …

… The search for means to delay aging has not ceased, … the aging process such that we may
be able to delay aging or potentially reverse it. Recent work has demonstrated that senescent …

… While cellular senescence in peripheral tissues has recently been … in brain aging is just
beginning to be explored. Recent data generated by several laboratories suggest that both aging …

… the brain, senescent cells naturally accumulate during aging … senescent cells in brain aging
and disorders. Here we highlight the phenotypical heterogeneity of different senescent brain …

… Thus, cellular senescence accumulation in the peripheral tissues, in both age-related and
… We hypothesized that peripheral cellular senescence contributes to brain aging and age-…

… nuclear and blood-brain-barrier integrity. Thus, cellular senescence can serve as a primary
… This review summarizes the concept of cellular senescence, its role in the aging brain, and …

… Understanding the role of senescence in neurocognitive … Such treatments could help
alleviate early brain aging in … on how cellular senescence plays a role in brain aging and age-…

… Thus, cellular senescence serves different … a senescent state remains unclear. In this review
we examine recent data that suggest that cellular senescence plays a role in brain aging and…

… of cellular senescence in aging and AD, the mechanisms that promote cell senescence and
how senescent … The potential mechanisms underlying brain cell senescence in AD will be …

… activation of aging-associated cellular senescence precedes … that emerges in adulthood
when aging-associated processes are … markers of cellular senescence are increased in brains of …