… of cellular senescence is an example of such mechanisms … a stable cell cycle arrest via
activation of cell cycle inhibitors … Here, we will discuss the implications of cellular senescence …

… and colleagues showed that cellular senescence was a … the senescence response was a
potent anti-cancer mechanism 4,5 . Since the 1960s, our understanding of cellular senescence, …

… cell and non-cell autonomous effects. Here, we summarize the mechanisms by which cellular
senescence can … of current potential pharmacological interventions for senescent cells, …

… Interventions such as rapamycin treatment … cellular senescence to extend cellular lifespan.
Here, we review the metabolic changes and potential metabolic regulators of the senescence …

… senescence-associated secretory phenotype (SASP), which is widely reported to promote
cancer. This review will look at the role of cellular senescence in … that show how senescence-…

… by changing life style behaviours, I also discuss non-drug interventions that may have the
potential to reduce telomere shortening via oxidative stress-suppressing mechanisms. …

… dysfunction, cellular senescence, stem cell exhaustion, … interventions that promote health
and longevity (such as caloric restriction, microbiota transplantation, and nutritional intervention…

… Cellular senescence is a state of stable cell cycle arrest … Cellular senescence is a biological
process characterized by a … stimuli (or SAGA, for senescence-associated growth arrest). …

… mechanism, limits tissue damage, and aids wound healing (12–16). Despite the protective
role of cellular senescence as a cellular … properties, therapeutic interventions could be also …

… As headway is being continuously made in the study of cellular senescence, this review …
to gather the most important and fundamental knowledge we have on senescence thus far. …