… (FGF) family of growth factors mediate their cellular responses by binding to and activating
the different isoforms encoded by the four receptor … Unlike other growth factors, FGFs act in …

… stimulation, and only a few signaling pathways are activated by direct interactions with the
… Cell signaling by EGF or FGF receptors. An abbreviated version of signaling by EGFR (left) …

… for differential expression of FGFs/FGFRs in … signaling cascade has an important role in
sperm development and maturation. Furthermore, we will demonstrate that FGF/FGFR signaling …

… between FGF and D2 of the second receptor in the complex, as well as by … for FGF binding
to the FGFR. In fact, deletion of D1 and the acid box enhances binding of the receptor to FGF …

… “Integrative Nuclear Fibroblast Growth Factor Receptor-1 (FGFR1) Signaling” (INFS) pathway,
… Activation of cell surface neurotransmitter, hormonal, or growth factor receptors stimulates …

… the nature of the ligand, the particular receptor, the signal transduction pathways utilized, or
the … of FGF signals with other signaling systems could contribute to the cellular response. In …

… within these dimeric receptors that stimulate tyrosine kinase activity and cell signaling. Some
… epidermal growth factor (EGF) binds to and activates pre-existing oligomers of its receptor ( …

… Third, binding of multiple FGF molecules to the same GAG yields oligomers of the growth
factor that may facilitate receptor dimerization and signal transduction. The interaction of FGFs …

… of the FGF receptor indicating the formation of a ternary complex consisting of HSPG, FGF
receptor … Moreover, the fine tuning of FGF signaling was demonstrated in a study showing that …

… factor (FGF) signals are transduced through FGF receptors to … genetic alteration of stem cell
signaling–related genes gives … , FGF, Notch, Hedgehog, and TGFβ/BMP signaling pathways …