Recent updates on novel therapeutic targets of cardiovascular diseases

M Afzal - Molecular and Cellular Biochemistry, 2021 - Springer
… also proceed to other cardiovascular diseases such as cardiac remodeling and myocardial
… drug targets from animal studies and evaluated them in the therapeutics of cardiac disorders, …

MicroRNAs as a therapeutic target for cardiovascular diseases

PK Mishra, N Tyagi, M Kumar… - Journal of cellular and …, 2009 - Wiley Online Library
… to treat a disease. This review embodies the recent progress made in microRNomics of
cardiovascular diseases and the future of miRNAs as a potential therapeutic target - the putative …

[HTML][HTML] Curcumin and cardiovascular diseases: Focus on cellular targets and cascades

AM Pourbagher-Shahri, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
… This study will help in identifying new molecular targets and evolve highly … cellular signaling
in CVDs. The molecular signaling cascades and targets connected to many cardiovascular

Oxidative stress in cardiovascular diseases: still a therapeutic target?

T Senoner, W Dichtl - Nutrients, 2019 - mdpi.com
Cardiovascular diseases (CVD) are complex entities with … for the manifestation of cellular
functions, whereas excessive … an additional target for preventing cardiovascular disease. …

Therapeutic targeting of cellular stress to prevent cardiovascular disease: a review of the evidence

AD Mooradian - American Journal of Cardiovascular Drugs, 2017 - Springer
… the major risk factors of cardiovascular disease (CVD) has … drugs with similar pharmacologic
targets have not been associated … Recent data suggest that reducing cellular stress such as …

Autophagy as a therapeutic target in cardiovascular disease

A Nemchenko, M Chiong, A Turer, S Lavandero… - … of molecular and cellular …, 2011 - Elsevier
… Here, we review the fundamental biology of autophagy and its role in a variety of forms of
cardiovascular disease. We discuss ways in which this evolutionarily conserved catabolic …

[HTML][HTML] Cellular senescence in cardiovascular diseases: a systematic review

C Hu, X Zhang, T Teng, ZG Ma, QZ Tang - Aging and disease, 2022 - ncbi.nlm.nih.gov
… cells) in age-related cardiovascular diseases. Then, we highlight the targets (SIRT1 and
mTOR) that regulating cellular senescence in cardiovascular disorders. Furthermore, we review …

Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment

F Olivieri, R Recchioni, F Marcheselli… - Current …, 2013 - ingentaconnect.com
… Senescence of endothelial and cardiac cells observed over normal aging, … diseases and
in particular, in cardiovascular disease (CVD). Although the molecular mechanisms of cellular

Inflammatory processes in cardiovascular disease: a route to targeted therapies

N Ruparelia, JT Chai, EA Fisher… - Nature reviews …, 2017 - nature.com
disease progression and injury, and promote healing 7,8,9,10 . Processes of inflammation
contribute to a broad range of cardiovascular diseases… molecular and cellular processes in the …

miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges

S Zhou, J Jin, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular disease (CVD) is one of the leading causes of death in the world, especially
in developed countries. As such, there is an urgent need to identify new prognostic and …