Cellular and molecular mechanisms underlying arterial baroreceptor remodeling in cardiovascular diseases and diabetes

H Tu, D Zhang, YL Li - Neuroscience Bulletin, 2019 - Springer
target to improve the prognosis of patients with cardiovascular diseases and diabetes. … is
a novel therapeutic approach for patients with cardiovascular diseases or diabetes, and has a …

SIRT3: a new regulator of cardiovascular diseases

W Sun, C Liu, Q Chen, N Liu, Y Yan… - … medicine and cellular …, 2018 - Wiley Online Library
… An important pathophysiological mechanism of cardiovascular disease is mitochondrial
damage and dysfunction. As shown in Table 1, SIRT3 plays important roles in cellular energy …

Forging the fate of cellular therapies for cardiovascular disease

RD Simari - Circulation research, 2017 - Am Heart Assoc
… The field of cell therapy for cardiovascular disease has progressed at an uneven rate and
will … will be subsets of cardiovascular disease that provide unique and specific targets for cell-…

Nitric oxide synthase inhibition and oxidative stress in cardiovascular diseases: possible therapeutic targets?

L Rochette, J Lorin, M Zeller, JC Guilland… - Pharmacology & …, 2013 - Elsevier
… The involvement of metal ions in disorders has made them an emerging target for therapeutic
interventions. Iron, an essential element for many important cellular functions in all living …

Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives

W Poller, S Dimmeler, S Heymans, T Zeller… - European heart …, 2018 - academic.oup.com
… to the identification of non-coding therapeutic targets in cardiovascular diseases (Figure 3). …
of human cardiovascular diseases constitute an indispensable first step towards target

The emerging landscape of circular RNA in cardiovascular diseases

M Zhou, JM Yang, X Xiong - Journal of Molecular and Cellular Cardiology, 2018 - Elsevier
targets for various cardiovascular diseases. Here, we review the biogenesis, properties
and biological function of circRNAs, and summarize their roles in cardiovascular disorders. …

The role of SARS‐CoV‐2 target ACE2 in cardiovascular diseases

H Zhu, L Zhang, Y Ma, M Zhai, L Xia… - Journal of Cellular …, 2021 - Wiley Online Library
SARS‐CoV‐2, the virus responsible for the global coronavirus disease (COVID‐19) pandemic,
attacks multiple organs of the human body by binding to angiotensin‐converting enzyme …

Cellular and cytokine-based inflammatory processes as novel therapeutic targets for the prevention and treatment of atherosclerosis

PJ Little, A Chait, A Bobik - Pharmacology & therapeutics, 2011 - Elsevier
Cardiovascular disease is the largest cause of morbidity and premature mortality and its
major underlying pathology is atherosclerosis. Atherosclerosis commences with the deposition …

[HTML][HTML] Recent advances on drug development and emerging therapeutic agents through targeting cellular homeostasis for ageing and cardiovascular disease

T Azam, H Zhang, F Zhou, X Wang - Frontiers in Aging, 2022 - frontiersin.org
cellular function. It is a driving factor in numerous age-related diseases including cardiovascular
diseases (… Cardiomyopathies, hypertension, ischaemic heart disease, and heart failure …

[HTML][HTML] Reactive oxygen species and angiotensin II signaling in vascular cells: implications in cardiovascular disease

RM Touyz - Brazilian journal of medical and biological research, 2004 - SciELO Brasil
… and cellular function and what the implications are in vascular function and remodeling in
cardiovascular diseases… by ROS that involve perturbations in cellular redox state and oxidative …