… roles that NF-κB might play in disease processes. In particular, we focus on how NF-κB affects
… presenting interesting implications on how NF-κB proteins mediate cellular transformation. …

… This finding not only further underscores the importance of NF-κB in HTLV-I-mediated T-cell
transformation but also implicates transition from Tax-dependent to Tax-independent NF-κB …

… family transcription factors in oncogenic transformation stem … , it transforms chicken
haematopoietic cells of B cell, T cell, … to the cellular c-rel and differs from its cellular counterpart by …

… To determine whether NF-κB is required for cellular transformation controlled by oncogenic
… the inhibition of NF-κB would affect the ability of Ras to cause formation of transformed foci in …

… Activation of NF-κB, by loss of p53, caused an increase in … cell transformation and acceleration
of aerobic glycolysis in p53-deficient cells were suppressed in the absence of p65/NF-κB …

We have previously demonstrated an involvement of MEK5 and ERK5 in RafBXB-stimulated
focus formation in NIH3T3 cells. We find here that MEK5 and ERK5 cooperate with the …

… by NF-κB that is critical for cellular transformation. … cellular transformation process, levels
of the primary let7a, let7c, and let7e RNAs are unaffected by (Figure 3E), suggesting that NF-κB …

… and EMT in the malignant transformation caused by CSE were investigated with … -κB (NF-κB),
which suppressed miR-200c expression and promoted EMT and cellular transformation. …

… of signaling molecules in cellular changes. Chronic exposure to arsenite increased cellular
levels of … by activating ERK/NF-κB and promoted cellular transformation. We also identified a …

… The second takes us back to the initial discovery of c-rel as a proto-oncogene: how does
activated c-Rel cause cellular transformation? The key role of the v-Rel dimer acting as a …