The abscopal effect 67 years later: from a side story to center stage

S Demaria, SC Formenti - The British Journal of Radiology, 2020 - academic.oup.com
… systemic, abscopal effects. Here, we will review the history and mechanisms of the abscopal
effect of radiation and discuss some of the barriers to achieving abscopal responses. Finally…

[HTML][HTML] The abscopal effect in the era of checkpoint inhibitors

O Kodet, K Němejcova, K Strnadová… - International Journal of …, 2021 - mdpi.com
abscopal effect is based on these principles of immune system surveillance [15]. The abscopal
effect … The term “abscopal” (from Latin, “ab”—away from, “scopus”—target) was used first (…

[HTML][HTML] Abscopal effect in a stage IV melanoma patient who progressed on pembrolizumab

JM Tsui, C Mihalcioiu, FL Cury - Cureus, 2018 - ncbi.nlm.nih.gov
… We believe this to be a case of abscopal effect witnessed during the delivery of radiotherapy…
This study also showed that the abscopal effect appears to be associated with a moderately …

[HTML][HTML] The abscopal effect: a review of pre-clinical and clinical advances

JR Janopaul-Naylor, Y Shen, DC Qian… - International journal of …, 2021 - mdpi.com
… as the abscopal effect. However, the occurrence of systemic anti-tumor effects was deemed
… radiation in combination may enhance the abscopal response. Increasing numbers of cases …

The abscopal effect: systematic review in patients with brain and spine metastases

DJ Pangal, B Yarovinsky, T Cardinal… - Neuro-Oncology …, 2022 - academic.oup.com
… to identify all studies which assessed the abscopal effect in patients with treated metastatic
… reported the abscopal effect in patients (case studies) or if the abscopal effect was explicitly …

The systemic immunostimulatory effects of radiation therapy producing overall tumor control through the abscopal effect

MA D'Andrea, GK Reddy - Journal of Radiation Oncology, 2019 - Springer
… Alterations in the microenvironment then prompt reactivation of the immune response, a
phenomenon called an abscopal effect of radiation therapy. The abscopal effect of radiation was …

[HTML][HTML] Abscopal effect of radiotherapy combined with immune checkpoint inhibitors

Y Liu, Y Dong, L Kong, F Shi, H Zhu, J Yu - Journal of hematology & …, 2018 - Springer
effect of RT and immune checkpoint blockade and discuss some published studies on the
abscopal effect … identify the potential predictors of the abscopal effect to help identify the most …

[HTML][HTML] Abscopal effect of radiotherapy in the immunotherapy era: systematic review of reported cases

N Dagoglu, S Karaman, HB Caglar, EN Oral - Cureus, 2019 - ncbi.nlm.nih.gov
… ago, the abscopal effect is revisited today. One rationale is that the abscopal effect is often
… Here, we give an overview of the clinical data on the abscopal effect, generated by a …

Abscopal, immunological effects of radiotherapy: narrowing the gap between clinical and preclinical experiences

N Brix, A Tiefenthaller, H Anders, C Belka… - Immunological …, 2017 - Wiley Online Library
… We will briefly outline the history of RT-induced abscopal effects as well as the RT-mediated
activation of the immune system, and we will present and discuss preclinical and clinical …

[HTML][HTML] Experimental model for the irradiation-mediated abscopal effect and factors influencing this effect

K Baba, M Nomura, S Ohashi, T Hiratsuka… - American journal of …, 2020 - ncbi.nlm.nih.gov
… , though the factors that influence the abscopal effect are not well understood. The aim of …
abscopal effect. Here, we established a mouse model in which we induced the abscopal effect. …